ID F4WFB2_ACREC Unreviewed; 337 AA.
AC F4WFB2;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 {ECO:0000313|EMBL:EGI67163.1};
GN ORFNames=G5I_04319 {ECO:0000313|EMBL:EGI67163.1};
OS Acromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex octospinosus
OS echinatior).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Acromyrmex.
OX NCBI_TaxID=103372 {ECO:0000313|Proteomes:UP000007755};
RN [1] {ECO:0000313|EMBL:EGI67163.1}
RP NUCLEOTIDE SEQUENCE.
RA Nygaard S., Zhang G.;
RT "The genome of the leaf-cutting ant Acromyrmex echinatior suggests key
RT adaptations to social evolution and fungus farming.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL888115; EGI67163.1; -; Genomic_DNA.
DR AlphaFoldDB; F4WFB2; -.
DR STRING; 103372.F4WFB2; -.
DR eggNOG; KOG3704; Eukaryota.
DR InParanoid; F4WFB2; -.
DR Proteomes; UP000007755; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR037359; NST/OST.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR10605:SF73; HEPARAN SULFATE 3-O SULFOTRANSFERASE-B, ISOFORM A; 1.
DR PANTHER; PTHR10605; HEPARAN SULFATE SULFOTRANSFERASE; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR637359-3};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007755};
KW Transferase {ECO:0000313|EMBL:EGI67163.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 110..311
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
FT REGION 56..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 118
FT /note="For sulfotransferase activity"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-1"
FT BINDING 118..122
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 199
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 207
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT DISULFID 306..318
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-3"
SQ SEQUENCE 337 AA; 38956 MW; 991EF945D1F8EEA4 CRC64;
MELRKGSWKI VILVCALVIY LWMLFIDHSH VLTDISQKIT LQKTRVPSRT VLYQSSDRSK
IEDVPPDGRT DSKKSQFLSP RNMSGTLEGG ISEYQTLKQQ GLLPSRQLPT ALIIGVKKGG
TRALLEFLRL HPAIRAAGSE VHFFDHHYVK GFRWYRRRMP PTLIGQITME KTPSYFVTSE
VPKRVKHMNP GMKLIVVVRD PVTRAISDYT QVKSKRRKMP RFEDLAFLNG SKIVDTSWMP
LKIGVYVRHL ERWLQYFPLS QFLFVSGERL IADPVTEVTR VQDFLGLKRV ICEKHFYFNA
TKGFPCLLKS EDRATPHCLG RIVENPSQKE FPDHMEK
//
