ID   F4WT58_ACREC            Unreviewed;       827 AA.
AC   F4WT58;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=valine--tRNA ligase {ECO:0000256|ARBA:ARBA00013169};
DE            EC=6.1.1.9 {ECO:0000256|ARBA:ARBA00013169};
DE   AltName: Full=Valyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00029936};
GN   ORFNames=G5I_09033 {ECO:0000313|EMBL:EGI62671.1};
OS   Acromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex octospinosus
OS   echinatior).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Acromyrmex.
OX   NCBI_TaxID=103372 {ECO:0000313|Proteomes:UP000007755};
RN   [1] {ECO:0000313|EMBL:EGI62671.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Nygaard S., Zhang G.;
RT   "The genome of the leaf-cutting ant Acromyrmex echinatior suggests key
RT   adaptations to social evolution and fungus farming.";
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|ARBA:ARBA00005594, ECO:0000256|RuleBase:RU363035}.
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DR   EMBL; GL888331; EGI62671.1; -; Genomic_DNA.
DR   AlphaFoldDB; F4WT58; -.
DR   STRING; 103372.F4WT58; -.
DR   eggNOG; KOG0432; Eukaryota.
DR   InParanoid; F4WT58; -.
DR   Proteomes; UP000007755; Unassembled WGS sequence.
DR   GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004832; F:valine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006438; P:valyl-tRNA aminoacylation; IEA:InterPro.
DR   CDD; cd07962; Anticodon_Ia_Val; 1.
DR   CDD; cd00817; ValRS_core; 1.
DR   Gene3D; 3.40.50.620; HUPs; 2.
DR   Gene3D; 3.90.740.10; Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain; 1.
DR   InterPro; IPR001412; aa-tRNA-synth_I_CS.
DR   InterPro; IPR002300; aa-tRNA-synth_Ia.
DR   InterPro; IPR033705; Anticodon_Ia_Val.
DR   InterPro; IPR013155; M/V/L/I-tRNA-synth_anticd-bd.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR   InterPro; IPR009008; Val/Leu/Ile-tRNA-synth_edit.
DR   InterPro; IPR002303; Valyl-tRNA_ligase.
DR   PANTHER; PTHR11946:SF117; VALINE--TRNA LIGASE; 1.
DR   PANTHER; PTHR11946; VALYL-TRNA SYNTHETASES; 1.
DR   Pfam; PF08264; Anticodon_1; 1.
DR   Pfam; PF00133; tRNA-synt_1; 1.
DR   PRINTS; PR00986; TRNASYNTHVAL.
DR   SUPFAM; SSF47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases; 1.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR   SUPFAM; SSF50677; ValRS/IleRS/LeuRS editing domain; 1.
DR   PROSITE; PS00178; AA_TRNA_LIGASE_I; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW   ECO:0000256|RuleBase:RU363035};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363035};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363035};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU363035};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW   ECO:0000256|RuleBase:RU363035};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007755}.
FT   DOMAIN          2..537
FT                   /note="Aminoacyl-tRNA synthetase class Ia"
FT                   /evidence="ECO:0000259|Pfam:PF00133"
FT   DOMAIN          591..730
FT                   /note="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase
FT                   anticodon-binding"
FT                   /evidence="ECO:0000259|Pfam:PF08264"
SQ   SEQUENCE   827 AA;  95349 MW;  8DB0B04C1C211ADF CRC64;
     MVLPPPNITG ILHLGHALTV IIQDVLARWH RMKGHPVLWI PGLDHAGIAT QAIVERTLQH
     TRNITRYDMG RDEFTQLIWQ WKAEKAAIIK QQLKALGATL DWDREYFTID ELFNSSKFYF
     FYFTEEELIV ATTRPETIFG DVAIAVHPND DRYSRYIGRY VFHPIRETFI PIIADSSVKR
     EFGTGAVKIT PAHDRLDYNI AKRHDLPVIC VIDEGGNMTD ACKEFKGVPR FITRKRLMDQ
     LSVRGLVKGV EDNHRMTLPL CSRTHDVIEY LPKEQWFLRC TAMAKRAYEA VANGELKIYP
     NEDGIYEQMW YNWLENHKYR DWCVSRQLWW GHRIPAYSII HGNGKDNDND IFSDSNNTTS
     WIIARSEEEA HSLAQEKYGN TVNLRQDPDV LDTWFSSTVV PFATLGWPEN TEDMARHYPL
     TLMETGHDIL MFWVARMVML SLELTQRLPF KEVLLHGVLC DGNGKKMSKS SGNVISPENI
     INGCTFEELN EQARLSHAAG ILSAEELQRT LRVNTKTYSM GIPDCGADAL RLSLCARNIK
     NHTISFDVDD CRTSKYFCNK IWQASKYVLL MTKEDQQRHE NVEKESLNDL DRWILSRLSW
     MVEIVNNAFV ERNFHKAITA IRQFLYYEFC DFYVEGTKFG FRSGNSAGHS NTLAKCLEVS
     LRILAPVTPY LSDDLYVRLA KKGLPGFLSV ASLLETSYPM PYEFKHLRDI RLEERICELV
     DVTNAIRSCM ANVSKKSNPE VNILVNNVRD YNFYRENVNL IKGASKIWNV PIHLIESAND
     SNFNRMMTRD NNSDGDGICT VQYMHTNDCS LLITVMVSRK MRSHTLI
//