ID F4WWJ0_ACREC Unreviewed; 1396 AA.
AC F4WWJ0;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Protein still life, isoforms C/SIF type 2 {ECO:0000313|EMBL:EGI61421.1};
GN ORFNames=G5I_10304 {ECO:0000313|EMBL:EGI61421.1};
OS Acromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex octospinosus
OS echinatior).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Acromyrmex.
OX NCBI_TaxID=103372 {ECO:0000313|Proteomes:UP000007755};
RN [1] {ECO:0000313|EMBL:EGI61421.1}
RP NUCLEOTIDE SEQUENCE.
RA Nygaard S., Zhang G.;
RT "The genome of the leaf-cutting ant Acromyrmex echinatior suggests key
RT adaptations to social evolution and fungus farming.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL888408; EGI61421.1; -; Genomic_DNA.
DR STRING; 103372.F4WWJ0; -.
DR eggNOG; KOG3519; Eukaryota.
DR InParanoid; F4WWJ0; -.
DR Proteomes; UP000007755; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd01230; PH1_Tiam1_2; 1.
DR CDD; cd01255; PH2_Tiam1_2; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 6.10.140.680; -; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR003116; RBD_dom.
DR InterPro; IPR043537; Tiam1/Tiam2/Sif.
DR InterPro; IPR040655; TIAM1_CC-Ex.
DR PANTHER; PTHR46001:SF2; PROTEIN STILL LIFE, ISOFORM SIF TYPE 1; 1.
DR PANTHER; PTHR46001; TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF02196; RBD; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR Pfam; PF18385; Tiam_CC_Ex; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00233; PH; 2.
DR SMART; SM00455; RBD; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50898; RBD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007755}.
FT DOMAIN 216..329
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 501..568
FT /note="RBD"
FT /evidence="ECO:0000259|PROSITE:PS50898"
FT DOMAIN 584..660
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 795..989
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 467..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 764..784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1189..1282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1348..1396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..485
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1189..1224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1225..1244
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1245..1259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1260..1282
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1367..1396
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1396 AA; 158757 MW; DDD9350F69FC2FD7 CRC64;
MVEPRWSIKC TNSTLDLLDP SDDYTDLKTQ HRRRCWKYFC WCRRHTISVI CINESRKLYW
FNCRNVQEKV TYGSGEGYYH KLLRLVNGAL NAWAQRYIDG LSVARREIML RINGSAENNM
KLLKEGCYCH YHPHMTADAC NADFLRRVVS FWADESLRGI RERLRGMMNI TKKMSDDDRM
SLTTAVSDDD DGESAINSPY RKQTGTAAAS FNCTGAVRKA GFLSVKKWLL RKKHQIELAK
KRGWRGYWVC LKGTTLLFYP CDSQESRAME AAPKHLIIVD GAIMQPIPEH PKKDYIFCLS
TAFGDAYLFQ APCQVELENW VNSIHSACAA AFARHRGKTG TLHLLQEEIF RLEKAIESDH
KMKHMADLQQ SVVSDVDTKQ QINNQIVQWE ENLERLHCEQ FRLRCYMASL QSGELPNPKS
LLTHVSRATK QTLNKLGVFT VSSFHAFICA RSPSLLNNLL AGRGATKRRP PLLSRSNSGS
SRRSLQISSR DEEKSVKVSV PENQVRSSGH RLVSVFLRDA MTVEEFLASA CTRKNLNPME
HFVRVKKRRD MEDHNYFVPH RTDLIETYLH THEIVEVCAK ILYQVELQRN TLEQMWGFSV
EAELIENSDR QDELCCYVSR VEDKSVAMQN GIIKGDEIMV INGAIVSDLD MMYLESVLQE
EVGLCMMMRS SRTEPPDLTG IMRVTDDIIE SLVCPPPPTD PPVISEEMIS GLIVPAPGWS
KENIMQECSS ASHADNKQSS RTNSFEIENL LKTAEQVTVI CRSPGETRKS SPTGSVVSSH
SQALTPSRQL SDAEKLKKVI LELIETERTY VKNLNNLLEN YLEPLKRETF LSNAEINALF
GNIQEIVTFQ RQFLQNLDHA IEMEADFNSF DHPSQFKGVL FSIGSAFLYY VNHFKLYSSF
CASHSKAQKV LHPNEGNQAL QEFLQARNPR QQHSSTLESY LIKPIQRILK YPLLLQQLRN
LTDERSEEHQ HLIEALKGME KVAEHINEMQ RIHEEYGAIF DHLFRQHQKS CKQPIDLSPG
DLLYYGGVEW LNISDFLGKI KKGLELHAMC FVFKSAVVFL CKERLRQKKK LMGVSTKANS
SEVEIIRYQV LIPVTEVQVR ASSAKDMESH FLWELIHLRS QLQRRSEKVY VLSNSTTEFR
NAFLKTIRQI IRESVRNMSI PSTKQNLSQA PMSMAPRMST GHVEKFNKQQ IGQGQTQNGN
GVTGTLSKKA MKQQLLSSSQ KRKYSHSKQP VEHESSEDKD QEDAPAPQQQ TFRSRSKTIS
DTSGEAKVEM DSGTKSEGEE DSQAFLGEKK TTLGRTPNHL TLSTTSTISA GSTGSQARLI
QSSHQPENYQ PITVKELGSP IWKPRELPSL GEATTLPRKG KSAGEFADMS SSHSASRKSL
IEINNSAQQP NFNNHV
//
