ID F4WY56_ACREC Unreviewed; 799 AA.
AC F4WY56;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=G-protein coupled receptor Mth2 {ECO:0000313|EMBL:EGI60813.1};
GN ORFNames=G5I_10913 {ECO:0000313|EMBL:EGI60813.1};
OS Acromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex octospinosus
OS echinatior).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Acromyrmex.
OX NCBI_TaxID=103372 {ECO:0000313|Proteomes:UP000007755};
RN [1] {ECO:0000313|EMBL:EGI60813.1}
RP NUCLEOTIDE SEQUENCE.
RA Nygaard S., Zhang G.;
RT "The genome of the leaf-cutting ant Acromyrmex echinatior suggests key
RT adaptations to social evolution and fungus farming.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 2 family. Mth
CC subfamily. {ECO:0000256|ARBA:ARBA00008979}.
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DR EMBL; GL888439; EGI60813.1; -; Genomic_DNA.
DR AlphaFoldDB; F4WY56; -.
DR eggNOG; ENOG502R7A7; Eukaryota.
DR InParanoid; F4WY56; -.
DR Proteomes; UP000007755; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR CDD; cd15039; 7tmB3_Methuselah-like; 1.
DR Gene3D; 2.170.180.11; Methuselah ectodomain, domain 2; 2.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 2.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR023311; Methusela_ecto_dom_2.
DR InterPro; IPR010596; Methuselah_N_dom.
DR InterPro; IPR036272; Methuselah_N_sf.
DR PANTHER; PTHR47154; G-PROTEIN COUPLED RECEPTOR MTH-RELATED; 1.
DR PANTHER; PTHR47154:SF2; G-PROTEIN COUPLED RECEPTOR MTH-RELATED; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF06652; Methuselah_N; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR SUPFAM; SSF63877; Methuselah ectodomain; 2.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:EGI60813.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007755};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..799
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003319045"
FT TRANSMEM 227..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 468..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 501..518
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 578..602
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..651
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 681..702
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 708..730
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 465..732
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 799 AA; 91275 MW; B34829CE3166BAC9 CRC64;
MGGRSVSFNL AVLLAACGTL IADDTGDAAD GLSLINDPRC SPSFSVILSL ESNGAASRSL
ENGSFIYDGI LYPAELRWTD GNVTYGCICR SRNCIRKCCG DDEILRNKSY NSEICQKMPR
NDTELITEIP HLRLSRNQMT KEIQHIENLK NYFYLVQDNV CPPGQQYYTL NPDDDSDEQI
ILQANGSFVD TAGKISPFWN YCIDWKMTVD RIGVLVCYTP EEEAKDFHYH MGIIVSIPFL
IATFLVYAIT PELRNLYGKT LMCYVICLII AYVFLILANY IYMSPIRVLC FSTALFIAFH
AVLIAAATFE SDQTKEEPEE SKWKENFIVP HVYLEKTIGI NSSGDSSGKP RMSLCCRVDT
FLNGDNCVEA TMNGTEAVQL PVIYEMDLIS ANVTASDKYF DFVIWNPCAG MKRYSLNPRV
YEDDEWYLLS NGLLNYYQYC LARVKSYEYP EYMVFFCDET IEDDDGIIYS YGMLASVPFL
VVTYVIYWLL PELRNLHGLT LRGYVGCLAM AYSILGVLQL TPQEQIPNGI CITIAFIIHF
SFLASFFWLN VMCFDIWWTF GGFRSLQGSV KQRERKKFII YSIYAWGSAS LLSIICAIMD
FVPSVPKELI RPEIGVTKCW FNTDEARALY FYGPMGVTVI CNICLFISTA LKIVRHKKDT
AHHLRGSESR RHDDNKQWFN LYLKLFIVMG INWSMEIVSW LFKSAPPYIW YLTDLTNTLQ
GLIIFIIFVW KKKIKRLLLK RFGYQDRDFF SRNSTRSGNH SSASRTCTTT SGIISLQEKV
NPYVQTNCRA KSSSDEVDS
//
