ID F4X781_ACREC Unreviewed; 495 AA.
AC F4X781;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Fork head domain-containing protein crocodile {ECO:0000313|EMBL:EGI57693.1};
GN ORFNames=G5I_14219 {ECO:0000313|EMBL:EGI57693.1};
OS Acromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex octospinosus
OS echinatior).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Acromyrmex.
OX NCBI_TaxID=103372 {ECO:0000313|Proteomes:UP000007755};
RN [1] {ECO:0000313|EMBL:EGI57693.1}
RP NUCLEOTIDE SEQUENCE.
RA Nygaard S., Zhang G.;
RT "The genome of the leaf-cutting ant Acromyrmex echinatior suggests key
RT adaptations to social evolution and fungus farming.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR EMBL; GL888828; EGI57693.1; -; Genomic_DNA.
DR RefSeq; XP_011066786.1; XM_011068484.1.
DR AlphaFoldDB; F4X781; -.
DR STRING; 103372.F4X781; -.
DR EnsemblMetazoa; XM_011068484.1; XP_011066786.1; LOC105153572.
DR GeneID; 105153572; -.
DR KEGG; aec:105153572; -.
DR eggNOG; KOG2294; Eukaryota.
DR InParanoid; F4X781; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000007755; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd20044; FH_FOXC1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR047391; FOXC1/C2-like_FH.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829:SF401; FORKHEAD BOX C1-A-RELATED; 1.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000007755}.
FT DOMAIN 69..163
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 69..163
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 176..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 323..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..193
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..362
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 495 AA; 54034 MW; 88C315497B169A2F CRC64;
MHTLFSEQNA YYRHATVPMG MGAPSYPAVG APGSYYEQYR YGGYATATGY PVSGIGQQHI
HHAGKDMVKP PYSYIALIAM AIQNAPDKKI TLNGIYQFIM DRFPYYRENK QGWQNSIRHN
LSLNECFVKV PRDDKKPGKG SYWSLDPDSY NMFDNGSYLR RRRRFKKKDA LKEKEEALKR
QGILPEKRQE DVKSSSSQVA LPPPSDASTK KLGGGLEVTG LCKPKREPVN DNHCMAAAAA
AAAAVQASKY GLHSPIQEDK TTTATVAAPG QSVIQTALGH QVHQAHQVHQ ESIQDVSMAG
LDPTSFSVDA LMTTRENNAG LMTRDNQHHS HHPHGLQHPH SIMSSRESMG SGSRDLSSAG
TTTTTTTAAV AAMMATSGYG HTSTVSRGNA SPPGTMYTPY CAPAATGYAI MDHEYNTARN
HASNAVGHSQ WYQDASPDTA IYQDTQSPSC QLYRSSPPTP LSTGAAPSPP LYHRYYQDCN
AVNTSGNLPI TLQKY
//
