ID F4XXC2_9CYAN Unreviewed; 636 AA.
AC F4XXC2;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Retron-type reverse transcriptase {ECO:0000313|EMBL:EGJ30781.1};
GN ORFNames=LYNGBM3L_46840 {ECO:0000313|EMBL:EGJ30781.1};
OS Moorena producens 3L.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Moorena.
OX NCBI_TaxID=489825 {ECO:0000313|EMBL:EGJ30781.1, ECO:0000313|Proteomes:UP000003959};
RN [1] {ECO:0000313|Proteomes:UP000003959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3L {ECO:0000313|Proteomes:UP000003959};
RX PubMed=21555588; DOI=10.1073/pnas.1101137108;
RA Jones A.C., Monroe E.A., Podell S., Hess W.R., Klages S., Esquenazi E.,
RA Niessen S., Hoover H., Rothmann M., Lasken R.S., Yates J.R.III.,
RA Reinhardt R., Kube M., Burkart M.D., Allen E.E., Dorrestein P.C.,
RA Gerwick W.H., Gerwick L.;
RT "Genomic insights into the physiology and ecology of the marine filamentous
RT cyanobacterium Lyngbya majuscula.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:8815-8820(2011).
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DR EMBL; GL890946; EGJ30781.1; -; Genomic_DNA.
DR RefSeq; WP_009149158.1; NZ_MKZR01000001.1.
DR AlphaFoldDB; F4XXC2; -.
DR eggNOG; COG3344; Bacteria.
DR HOGENOM; CLU_013584_15_4_3; -.
DR OrthoDB; 435986at2; -.
DR Proteomes; UP000003959; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR CDD; cd01651; RT_G2_intron; 1.
DR Gene3D; 1.10.30.50; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR030931; Group_II_RT_mat.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR InterPro; IPR013597; Mat_intron_G2.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR025960; RVT_N.
DR NCBIfam; TIGR04416; group_II_RT_mat; 1.
DR PANTHER; PTHR34047:SF8; GROUP II INTRON-ASSOCIATED OPEN READING FRAME; 1.
DR PANTHER; PTHR34047; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF08388; GIIM; 1.
DR Pfam; PF01844; HNH; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF13655; RVT_N; 1.
DR SMART; SM00507; HNHc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:EGJ30781.1};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:EGJ30781.1};
KW Transferase {ECO:0000313|EMBL:EGJ30781.1}.
FT DOMAIN 100..344
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT REGION 584..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..614
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 636 AA; 73503 MW; 1734A610BA736F18 CRC64;
MEKIEPQPYG NGIVTKQTTD WHAINWKRAY RTVRKLRRRI FRATREGNWK KVNKLQRLAL
RSYSNILISV KQATQVNSGK KTAGIDGKKK LNPAERGLMV DSLTTYKTWK PIPTKRIYIP
KSNGKKRPLG IPCITDRCLQ GIVKNALEPS WEAMFEPVSY GFRPGRSTHD ARQRIFLNIK
GENNKKWWVV DADISGCFDN IAHEPLLEAI GSFPATKLIK EWLKAGYIHK GTFYDTEQGT
PQGGIISPLY ANIALHGLEK ELGIKYYWCK DKKAKNGGNW KNRTPRTYVR FADDFVILTE
SKEDAVNALK IAEEWLSKKG LTLSFEKTRI SHLTTGFDFL GWNFRKHNTS TRKSGYITII
KPSDKNVAKF KTKLKEEFKK VRSAPQEVVI KRLNPIIRGW GNYHSGAVSS EIFNKIDSYI
FWKLTRWGLR KHQKSREWLY KKYFGKLCPG RDDKWVFGER KVYLTKLAWV NIERHTQVTH
THSPDDPELK EYWEKRENKQ KQKTARNRLS NGKNKIANRQ NYICPVCNQT LGRYDNVHLH
HITPKKDGGT DKYDNLIYLH NDCHHSIHAL GATNPEIQQM LKMGLKKPSK KKGQKPKGTN
PDSRKSKSQK KTCSKEVGRA VCLETRSHGA LGTKRE
//
