ID F5GU78_CAEEL Unreviewed; 579 AA.
AC F5GU78;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 78.
DE SubName: Full=Lon proteolytic domain-containing protein {ECO:0000313|EMBL:CCA65529.1};
GN Name=lido-17 {ECO:0000313|EMBL:CCA65529.1,
GN ECO:0000313|WormBase:C06C3.8a};
GN ORFNames=C06C3.8 {ECO:0000313|WormBase:C06C3.8a}, CELE_C06C3.8
GN {ECO:0000313|EMBL:CCA65529.1};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCA65529.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCA65529.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCA65529.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX284602; CCA65529.1; -; Genomic_DNA.
DR RefSeq; NP_001254207.1; NM_001267278.1.
DR AlphaFoldDB; F5GU78; -.
DR SMR; F5GU78; -.
DR STRING; 6239.C06C3.8a.1; -.
DR MEROPS; S16.A09; -.
DR PaxDb; 6239-C06C3-8a; -.
DR EnsemblMetazoa; C06C3.8a.1; C06C3.8a.1; WBGene00007378.
DR GeneID; 174487; -.
DR AGR; WB:WBGene00007378; -.
DR WormBase; C06C3.8a; CE46024; WBGene00007378; lido-17.
DR HOGENOM; CLU_471119_0_0_1; -.
DR PhylomeDB; F5GU78; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00007378; Expressed in adult organism and 2 other cell types or tissues.
DR ExpressionAtlas; F5GU78; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.230.10; -; 1.
DR InterPro; IPR005020; LIN-8.
DR InterPro; IPR008269; Lon_proteolytic.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR PANTHER; PTHR32020; LIN-8 DOMAIN CONTAINING-RELATED; 1.
DR PANTHER; PTHR32020:SF4; LIN-8 DOMAIN CONTAINING-RELATED; 1.
DR Pfam; PF03353; Lin-8; 1.
DR Pfam; PF05362; Lon_C; 1.
DR PRINTS; PR00830; ENDOLAPTASE.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT DOMAIN 44..128
FT /note="Lon proteolytic"
FT /evidence="ECO:0000259|Pfam:PF05362"
FT REGION 143..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..199
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..246
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 579 AA; 65276 MW; 0F6767143D9059DC CRC64;
MTQEMQQSME LSHEIVIANG HLFGIQGFTC NITLSLEQIG RTYNGVSMAL PFVLLIISAI
KKNSLRKDYV ATGDVSLAGA VLTVDYINNK IVGAINAGLK GVVIPAENGK DVKPFLKTQI
KVIEVTSIVD AWSTMIIPEM PNGDSGASNC GSLDGVRSVT RKGKTMKTMK SGLPHRNQIS
KESDRSRNSG SSTNDSLNDD RLLCGIIPGK QVKNNNEEHT LSQAHRGNLD DEQGSHRKRN
ECKQTDQKNE MTSMGECIGE VIREDYLVIN SSDNCRRPLY KQPCPYPPEE LPKPDPERKM
SHTEYLQLSE SPKLGVQKIG SKDVLLKKVI LNEISKSPAI WNTYKANGIY SEVAVNVFKR
TGKLLNIKLI QSIFKLAKDG LRNRLRDSIT EKLHNEADTE NHLWQWELYE FIRFYREITE
GWELRMRALV AKKHEGQLRV RESAECSDMI KDDKNLINID DERNMKLDHV RTDISDTSIV
QTCMDSSRLP SNDEHPGAKP TLIHHTTPSL DCQPTKHESI HSDFSKEMDQ LVNQATRIAR
EHPERAETLL KALFATVSTF DQEGYVCVED KKFTEKQSK
//
