ID F5GUF0_CAEEL Unreviewed; 217 AA.
AC F5GUF0;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 80.
DE SubName: Full=WH2 domain-containing protein {ECO:0000313|EMBL:CCA65600.1};
GN Name=wve-1 {ECO:0000313|EMBL:CCA65600.1,
GN ECO:0000313|WormBase:R06C1.3b};
GN ORFNames=CELE_R06C1.3 {ECO:0000313|EMBL:CCA65600.1}, R06C1.3
GN {ECO:0000313|WormBase:R06C1.3b};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCA65600.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCA65600.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCA65600.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284601; CCA65600.1; -; Genomic_DNA.
DR RefSeq; NP_001251762.1; NM_001264833.1.
DR AlphaFoldDB; F5GUF0; -.
DR IntAct; F5GUF0; 6.
DR PeptideAtlas; F5GUF0; -.
DR EnsemblMetazoa; R06C1.3b.1; R06C1.3b.1; WBGene00006958.
DR GeneID; 187639; -.
DR AGR; WB:WBGene00006958; -.
DR WormBase; R06C1.3b; CE45993; WBGene00006958; wve-1.
DR HOGENOM; CLU_036022_2_0_1; -.
DR OrthoDB; 616448at2759; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00006958; Expressed in embryo and 3 other cell types or tissues.
DR ExpressionAtlas; F5GUF0; baseline and differential.
DR GO; GO:0031209; C:SCAR complex; IBA:GO_Central.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0071933; F:Arp2/3 complex binding; IBA:GO_Central.
DR GO; GO:0034237; F:protein kinase A regulatory subunit binding; IBA:GO_Central.
DR GO; GO:0030036; P:actin cytoskeleton organization; IBA:GO_Central.
DR GO; GO:0007015; P:actin filament organization; ISS:WormBase.
DR GO; GO:0048598; P:embryonic morphogenesis; IGI:WormBase.
DR GO; GO:0008045; P:motor neuron axon guidance; IMP:WormBase.
DR GO; GO:0001764; P:neuron migration; IMP:WormBase.
DR GO; GO:2000601; P:positive regulation of Arp2/3 complex-mediated actin nucleation; IBA:GO_Central.
DR CDD; cd22057; WH2_WAVE; 1.
DR Gene3D; 6.10.280.150; -; 1.
DR InterPro; IPR003124; WH2_dom.
DR Pfam; PF02205; WH2; 1.
DR SMART; SM00246; WH2; 1.
DR PROSITE; PS51082; WH2; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:F5GUF0,
KW ECO:0007829|PeptideAtlas:F5GUF0};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT DOMAIN 152..169
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 1..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..118
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 217 AA; 22664 MW; 61DBE939D20BB99C CRC64;
MVAPIGMTMH HHPQQNVHPS QQRGGAPAAA RGSPNVKRPT EAPPPVNLDH LPPPDMSILS
IDDDDDDLPP PPPPLLMNTS IVHQLPAEAP STIQFVEPSA APPTNIPPPP PPPPPMVISS
AAASFAAPAP KPSADGEAAG TNSPVAPKQP DARSDLLAQI QSGIKLKKVQ RAEAEAAENA
ALEANNVAAI LKRRMDQVMG NDDSSSEEGA DDDEWDD
//
