ID F5GZ45_HUMAN Unreviewed; 180 AA.
AC F5GZ45;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 8.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Folate receptor beta {ECO:0000313|Ensembl:ENSP00000441547.1};
DE Flags: Fragment;
GN Name=FOLR2 {ECO:0000313|Ensembl:ENSP00000441547.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000441547.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000441547.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16554811; DOI=10.1038/nature04632;
RA Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT "Human chromosome 11 DNA sequence and analysis including novel gene
RT identification.";
RL Nature 440:497-500(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000441547.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the folate receptor family.
CC {ECO:0000256|ARBA:ARBA00007932}.
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DR EMBL; AP000593; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF455414; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; F5GZ45; -.
DR SMR; F5GZ45; -.
DR MassIVE; F5GZ45; -.
DR PeptideAtlas; F5GZ45; -.
DR ProteomicsDB; 24935; -.
DR Antibodypedia; 30818; 408 antibodies from 33 providers.
DR Ensembl; ENST00000539412.5; ENSP00000441547.1; ENSG00000165457.15.
DR UCSC; uc058fac.1; human.
DR HGNC; HGNC:3793; FOLR2.
DR VEuPathDB; HostDB:ENSG00000165457; -.
DR GeneTree; ENSGT00950000183144; -.
DR ChiTaRS; FOLR2; human.
DR Proteomes; UP000005640; Chromosome 11.
DR Bgee; ENSG00000165457; Expressed in gall bladder and 182 other cell types or tissues.
DR ExpressionAtlas; F5GZ45; baseline and differential.
DR InterPro; IPR004269; Folate_rcpt.
DR InterPro; IPR018143; Folate_rcpt-like.
DR PANTHER; PTHR10517; FOLATE RECEPTOR; 1.
DR PANTHER; PTHR10517:SF8; FOLATE RECEPTOR BETA; 1.
DR Pfam; PF03024; Folate_rec; 1.
PE 1: Evidence at protein level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Proteomics identification {ECO:0007829|MaxQB:F5GZ45,
KW ECO:0007829|PeptideAtlas:F5GZ45};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..180
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008414316"
FT DOMAIN 41..180
FT /note="Folate receptor-like"
FT /evidence="ECO:0000259|Pfam:PF03024"
FT NON_TER 180
FT /evidence="ECO:0000313|Ensembl:ENSP00000441547.1"
SQ SEQUENCE 180 AA; 20912 MW; F320CF7FDAD61B24 CRC64;
MLPAATEGQK DMVWKWMPLL LLLVCVATMC SAQDRTDLLN VCMDAKHHKT KPGPEDKLHD
QCSPWKKNAC CTASTSQELH KDTSRLYNFN WDHCGKMEPA CKRHFIQDTC LYECSPNLGP
WIQQVNQSWR KERFLDVPLC KEDCQRWWED CHTSHTCKSN WHRGWDWTSG VNKCPAGALC
//
