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Database: UniProt
Entry: F5HMK6_ANOGA
LinkDB: F5HMK6_ANOGA
Original site: F5HMK6_ANOGA 
ID   F5HMK6_ANOGA            Unreviewed;       274 AA.
AC   F5HMK6;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   23-MAY-2018, entry version 44.
DE   SubName: Full=AGAP001585-PC {ECO:0000313|EMBL:EGK97529.1};
DE   SubName: Full=Deoxynucleoside kinase {ECO:0000313|VectorBase:AGAP001585-PC};
GN   Name=1281587 {ECO:0000313|VectorBase:AGAP001585-PC};
GN   ORFNames=AgaP_AGAP001585 {ECO:0000313|EMBL:EGK97529.1};
OS   Anopheles gambiae (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Anophelinae; Anopheles.
OX   NCBI_TaxID=7165 {ECO:0000313|EMBL:EGK97529.1, ECO:0000313|Proteomes:UP000007062};
RN   [1] {ECO:0000313|EMBL:EGK97529.1, ECO:0000313|Proteomes:UP000007062, ECO:0000313|VectorBase:AGAP001585-PC}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEST {ECO:0000313|EMBL:EGK97529.1,
RC   ECO:0000313|Proteomes:UP000007062};
RX   PubMed=12364791; DOI=10.1126/science.1076181;
RA   Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA   Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA   Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B.,
RA   Lai Z., Kraft C.L., Abril J.F., Anthouard V., Arensburger P.,
RA   Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V.,
RA   Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S.,
RA   Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M.,
RA   Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I.,
RA   Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z.,
RA   Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R.,
RA   Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E.,
RA   Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F.,
RA   Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R.,
RA   Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C.,
RA   Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V.,
RA   Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D.,
RA   Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H.,
RA   Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A.,
RA   Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA   Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F.,
RA   Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S.,
RA   Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C.,
RA   Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.;
RT   "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL   Science 298:129-149(2002).
RN   [2] {ECO:0000313|EMBL:EGK97529.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EGK97529.1};
RG   The Anopheles Genome Sequencing Consortium;
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:EGK97529.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EGK97529.1};
RX   PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA   Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT   "The Anopheles gambiae genome: an update.";
RL   Trends Parasitol. 20:49-52(2004).
RN   [4] {ECO:0000313|EMBL:EGK97529.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EGK97529.1};
RX   PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA   Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA   Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT   "Update of the Anopheles gambiae PEST genome assembly.";
RL   Genome Biol. 8:R5-R5(2007).
RN   [5] {ECO:0000313|EMBL:EGK97529.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EGK97529.1};
RG   VectorBase;
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [6] {ECO:0000313|VectorBase:AGAP001585-PC}
RP   IDENTIFICATION.
RC   STRAIN=PEST {ECO:0000313|VectorBase:AGAP001585-PC};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   EMBL; AAAB01008987; EGK97529.1; -; Genomic_DNA.
DR   RefSeq; XP_003435883.1; XM_003435835.1.
DR   STRING; 7165.AGAP001585-PC; -.
DR   EnsemblMetazoa; AGAP001585-RC; AGAP001585-PC; AGAP001585.
DR   GeneID; 1281587; -.
DR   KEGG; aga:AgaP_AGAP001585; -.
DR   VectorBase; AGAP001585-RC; AGAP001585-PC; AGAP001585.
DR   eggNOG; KOG4235; Eukaryota.
DR   eggNOG; COG1428; LUCA.
DR   InParanoid; F5HMK6; -.
DR   KO; K05961; -.
DR   PhylomeDB; F5HMK6; -.
DR   Proteomes; UP000007062; Chromosome 2R.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0019206; F:nucleoside kinase activity; IEA:InterPro.
DR   InterPro; IPR002624; DCK/DGK.
DR   InterPro; IPR031314; DNK_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01712; dNK; 1.
DR   PIRSF; PIRSF000705; DNK; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007062};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007062}.
FT   DOMAIN       48    238       dNK. {ECO:0000259|Pfam:PF01712}.
FT   NP_BIND      51     59       ATP. {ECO:0000256|PIRSR:PIRSR000705-3}.
FT   NP_BIND     186    190       ATP. {ECO:0000256|PIRSR:PIRSR000705-3}.
FT   ACT_SITE    127    127       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000705-1}.
SQ   SEQUENCE   274 AA;  31319 MW;  E4CA1F1BF40B6154 CRC64;
     MLLKTVRLML RPAKSISCSQ LGRRNIHNMP PIASEKLGAS GKKPFTVFVE GNIGSGKTTF
     LNHFQKFNDI CLLTEPVEKW RNCGGVNLLD LMYKESHRWA MPFQTYVTLT MLDMHTCQTD
     KSVKLMERSL FSARNCFVES MLASGSLHQG MYNVLQEWYD FICCNIHIQA DLIVYLQTSP
     EVVYERMKQR ARSEESCVPL EYLKELHELH ENWLIHGASP RPAPVLVLNA DLDLNTIGAE
     YERSETSILK PILIENTNQH AILTSPAKRA KTDF
//
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