ID F5IWF1_9BACT Unreviewed; 1358 AA.
AC F5IWF1;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 24-JAN-2024, entry version 65.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=HMPREF9455_01418 {ECO:0000313|EMBL:EGK02461.1};
OS Dysgonomonas gadei ATCC BAA-286.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Dysgonomonadaceae;
OC Dysgonomonas.
OX NCBI_TaxID=742766 {ECO:0000313|EMBL:EGK02461.1, ECO:0000313|Proteomes:UP000004913};
RN [1] {ECO:0000313|EMBL:EGK02461.1, ECO:0000313|Proteomes:UP000004913}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-286 {ECO:0000313|EMBL:EGK02461.1,
RC ECO:0000313|Proteomes:UP000004913};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Pudlo N., Martens E.,
RA Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA Stolte C., Sykes S., Yandava C., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Dysgonomonas gadei ATCC BAA-286.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGK02461.1}.
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DR EMBL; ADLV01000017; EGK02461.1; -; Genomic_DNA.
DR RefSeq; WP_006798933.1; NZ_GL891981.1.
DR STRING; 742766.HMPREF9455_01418; -.
DR eggNOG; COG0745; Bacteria.
DR eggNOG; COG2205; Bacteria.
DR eggNOG; COG2207; Bacteria.
DR eggNOG; COG3292; Bacteria.
DR HOGENOM; CLU_000445_28_1_10; -.
DR OrthoDB; 717811at2; -.
DR Proteomes; UP000004913; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF07494; Reg_prop; 3.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000004913};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 784..803
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 835..1055
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1099..1214
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1248..1347
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT MOD_RES 1147
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1358 AA; 157002 MW; 136FAFAFF8186F20 CRC64;
MKYNSQINRL VLFTISIILS NSICAYSLRQ YSSKNGLSNS AILSMYQDKE GLMWFGSCEG
LNMFDGLKFQ VFMPSNEENI LSGNIIESIL EAEDNTLWIQ TNYGLDRLDK QLKTVRTFKE
FKGKNWVIKN TANDIFVVKN DNYLYYYVAK EDKFHNIYIE DLVFDDILQI VIDKENTLWV
FMKNGKYFSY NIHPDENRKP TLIKKNYFTN KENIIWCFYE DGIFYFVDDT YALYEFDPIS
KNKYYIHDIS AEVVKYGDIS SIIKYKDNYF IGFKNSGLII LQHIPEQKKR FSIYEVDIKS
GIFCLMKDKY QDIVWVGTDG QGVYMYYTDS YTIKSTLFRD IPHNINNPIR TFYLDDKNTL
WIGTKGDGIV SLGGYDIATG SQTTSTHFQT MNSLLKDNSV YTIVPSKKNI LWIGSEKGIN
YYSYKDKKIK NIDVSIDGKP VQYVHSICEF NDSTLWIATV GEGIVKARLG GDNDNPVISS
EKLFLFDEGK FSSNYFFTTY KENDSIIWFG NRGYGAYRIN NHTEDVETFT FDQNDKNQTL
NDIFSILKNK DGYWFGTSYG LARMYDDGKK QTFDKENGFP NNAIHGILQD YYNNLWLSTN
QGLIKFNIAQ NTFQTYRQHN ELEVTEFSDG AYFKHENTGV LFFGGINGFV TIIANEPAKE
DYSPSIQFNG LSIFGKENNI FDFLETKNGD KTLKLNYKQN FFSISFTAVD YIHGNDYTYF
YKLDELSTNW IDNGTSNTAA FTNISPGKYT LLVKYRNNIT GKESPVQFLF IDIVPPWYLT
NMAYLVYAIL SLCILFIIIR FSIKWYKMKK DNIIERLNRQ QREEIYESKL RFFTNITHEL
CTPLTLIYGP CEKILSYKNT DNYINKYATL IQHNAEKLNG LISELIEFRR LETGNKTLEI
RNLSVSELTR NITDSFTELA EAKGFEYEVS IEENVLWNTD SGCLSKVVTN LISNAFKYTS
DNGKIGFELF VKGRKLHIAV SNTGKGIKKE DIAKIFDRYT ILDNFEGLNK NKVSPRNGLG
LAICHNMVKL LEGEINVSST PNEVTVFTVI LPALEATDDS SAYDSTELSL IEETLPVNLE
NSPVPDDYIL PGYDKEKRTI MIVDDDPSML WFVTEIFIEQ YNVIPINDPK EVIPCLKKNL
PDLIISDIMM PDIDGLSLTA SIKADKLQNH IPLILLSAKN TEEDQIRGID SGAEVYITKP
FNVKYLEKVV ERLIKRKEDL QQYFSSALSS FEVSEGKLTH EEDRRFMEKV YEIIETNIAN
PDLSVETISS SLGYSTRQFY RRLKDITPKK TVDIIKEYKL DVVKRLLIST NLSVDEIMDR
TGFANRGNFF KIFFQKFETT PKKYREEVRK NAEKSKDI
//
