ID F5IY73_9BACT Unreviewed; 433 AA.
AC F5IY73;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=Mechanosensitive ion channel MscS domain-containing protein {ECO:0000259|Pfam:PF00924};
GN ORFNames=HMPREF9455_02040 {ECO:0000313|EMBL:EGK01659.1};
OS Dysgonomonas gadei ATCC BAA-286.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Dysgonomonadaceae;
OC Dysgonomonas.
OX NCBI_TaxID=742766 {ECO:0000313|EMBL:EGK01659.1, ECO:0000313|Proteomes:UP000004913};
RN [1] {ECO:0000313|EMBL:EGK01659.1, ECO:0000313|Proteomes:UP000004913}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-286 {ECO:0000313|EMBL:EGK01659.1,
RC ECO:0000313|Proteomes:UP000004913};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Pudlo N., Martens E.,
RA Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA Stolte C., Sykes S., Yandava C., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Dysgonomonas gadei ATCC BAA-286.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGK01659.1}.
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DR EMBL; ADLV01000022; EGK01659.1; -; Genomic_DNA.
DR RefSeq; WP_006799569.1; NZ_GL891982.1.
DR AlphaFoldDB; F5IY73; -.
DR STRING; 742766.HMPREF9455_02040; -.
DR eggNOG; COG0668; Bacteria.
DR HOGENOM; CLU_045354_1_0_10; -.
DR OrthoDB; 9775207at2; -.
DR Proteomes; UP000004913; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0071470; P:cellular response to osmotic stress; IEA:InterPro.
DR Gene3D; 2.30.30.60; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR030192; YbdG.
DR PANTHER; PTHR30414:SF0; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL YBDG; 1.
DR PANTHER; PTHR30414; UNCHARACTERIZED; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004913};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 203..271
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
SQ SEQUENCE 433 AA; 49695 MW; 80F2EBDC7D14B6B3 CRC64;
MDIEDLQSDY ESMTVSIARW MQETLSHLGV PEQWVEYVKL IVLLAIVTIT VYLLQLVVRK
ILTFVFHRVE KITTLSFFGY TINNKLPHYL ALVVPYSFVR GAIPIVFYDF KGLISPLIKL
TDIYLVFMVI WTVMALVRSF GDVLQEKPAF KNKPMKSYFQ VIQIILFIFG AVVVYAILTG
RSATAFFAAM GAASAVLLLM FKDSIMGFVG SIQITTNDMV QIGDWITMNK YGADGNVEEI
TLTTVKVRNF DKTITTIPTY ALISDSFQNW RGMQESGGRR FRRALNIKYD SIRFLTEEEI
EKFKKVDGLA DYIKEKQGIY AKLNKQTASD LPLNKHAITN CDLFMQYGIY YLRNHPNINK
DMTLLVRQLA STTQGLPIEL YTFTSTTIWA EYETILAEIM NHLISVVQYF GLTIYEESSG
SDDYNVYMKR MEQ
//
