ID F5L4Y5_CALTT Unreviewed; 379 AA.
AC F5L4Y5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Dicarboxylate/amino acid:cation symporter {ECO:0000313|EMBL:QZT32521.1};
DE SubName: Full=Sodium:dicarboxylate symporter {ECO:0000313|EMBL:EGL83598.1};
GN ORFNames=CathTA2_0848 {ECO:0000313|EMBL:EGL83598.1}, HUR95_08845
GN {ECO:0000313|EMBL:QZT32521.1};
OS Caldalkalibacillus thermarum (strain TA2.A1).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Caldalkalibacillus.
OX NCBI_TaxID=986075 {ECO:0000313|EMBL:EGL83598.1, ECO:0000313|Proteomes:UP000010716};
RN [1] {ECO:0000313|EMBL:EGL83598.1, ECO:0000313|Proteomes:UP000010716}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TA2.A1 {ECO:0000313|EMBL:EGL83598.1,
RC ECO:0000313|Proteomes:UP000010716};
RX PubMed=21685297; DOI=10.1128/JB.05035-11;
RA Kalamorz F., Keis S., McMillan D.G., Olsson K., Stanton J.A., Stockwell P.,
RA Black M.A., Klingeman D.M., Land M.L., Han C.S., Martin S.L., Becher S.A.,
RA Peddie C.J., Morgan H.W., Matthies D., Preiss L., Meier T., Brown S.D.,
RA Cook G.M.;
RT "Draft genome sequence of the thermoalkaliphilic Caldalkalibacillus
RT thermarum strain TA2.A1.";
RL J. Bacteriol. 193:4290-4291(2011).
RN [2] {ECO:0000313|EMBL:QZT32521.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TA2.A1 {ECO:0000313|EMBL:QZT32521.1};
RX PubMed=33030592;
RA de Jong S.I., van den Broek M.A., Merkel A.Y., de la Torre Cortes P.,
RA Kalamorz F., Cook G.M., van Loosdrecht M.C.M., McMillan D.G.G.;
RT "Genomic analysis of Caldalkalibacillus thermarum TA2.A1 reveals aerobic
RT alkaliphilic metabolism and evolutionary hallmarks linking alkaliphilic
RT bacteria and plant life.";
RL Extremophiles 24:923-935(2020).
RN [3] {ECO:0000313|EMBL:QZT32521.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TA2.A1 {ECO:0000313|EMBL:QZT32521.1};
RA de Jong S., van den Broek M., Merkel A., de la Torre Cortes P.,
RA Kalamorz F., Cook G., van Loosdrecht M., McMillan D.;
RL Submitted (AUG-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AFCE01000095; EGL83598.1; -; Genomic_DNA.
DR EMBL; CP082237; QZT32521.1; -; Genomic_DNA.
DR RefSeq; WP_007503416.1; NZ_CP082237.1.
DR AlphaFoldDB; F5L4Y5; -.
DR KEGG; cthu:HUR95_08845; -.
DR eggNOG; COG1301; Bacteria.
DR OrthoDB; 9768885at2; -.
DR Proteomes; UP000010716; Unassembled WGS sequence.
DR Proteomes; UP000825179; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF9; INTEGRAL MEMBRANE TRANSPORT PROTEIN-RELATED; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010716};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 31..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 379 AA; 39918 MW; B394525FA92B5C7F CRC64;
MRLIVKLLAG ITGGMLIGLY APEFFSRVFV TFKIIFGQFI GFIIPLIIVF FIASGISELG
KQSGKMLGLT SGLAYSSTLL AGILAYVVAV TVVPLLTGPA GEHGEEGAGL EPLFELTIEP
IVGVMTALIT AFVFGIGMTR VESPVLKQFF DQGKNIVELL IKRVIIPLLP LYIAGVFVDL
AAEGSIFPTL RAFGIVLLLA VLTHWVWLLM LYTGAGTLTG RNPFRALKTM LPAYFTAIGT
MSSAATIPVT LRQAKENKIK EHVADFAIPL SATIHLSGST ITLVLCSVAV MVLSSGLDLP
TLGTMLPFIL MLGVIMIAAP GVPGGAVMAA LGLLSTMLGF DEAALGLMIA LYMAQDSFGT
ACNVTGDGAL ALVVDKYSQ
//
