ID F5LQD0_9BACL Unreviewed; 666 AA.
AC F5LQD0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Penicillin-binding protein, transpeptidase domain protein {ECO:0000313|EMBL:EGL15462.1};
GN ORFNames=HMPREF9413_3958 {ECO:0000313|EMBL:EGL15462.1};
OS Paenibacillus sp. HGF7.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=944559 {ECO:0000313|EMBL:EGL15462.1, ECO:0000313|Proteomes:UP000003445};
RN [1] {ECO:0000313|EMBL:EGL15462.1, ECO:0000313|Proteomes:UP000003445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HGF7 {ECO:0000313|EMBL:EGL15462.1,
RC ECO:0000313|Proteomes:UP000003445};
RA Durkin A.S., Madupu R., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGL15462.1}.
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DR EMBL; AFDH01000116; EGL15462.1; -; Genomic_DNA.
DR RefSeq; WP_009676153.1; NZ_AFDH01000116.1.
DR AlphaFoldDB; F5LQD0; -.
DR OrthoDB; 9770103at2; -.
DR Proteomes; UP000003445; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000003445};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 68..264
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 317..651
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 666 AA; 73959 MW; A5878E2ED759F4F4 CRC64;
MKSPYTEQDP AKREADKRIH FTLRINIFFF ATFALFCVLI VKLSYLQFVK GPELQIAKTN
GMNTDTAIPP IRGNILSKDG VPIATSNSTE SLYFRVEGGT KNQDPIIETA KKLEKILGDL
GDKNLPKMTM ENIMKAMDLD FDINKQKIKP KTPYSEPRRI KANLNKEEVA YLLSHRDELH
GVEVVEESIR MYDQRKIAAQ LVGYLKKYDD TANLNFYKSR QDQGYLLRET VGFDGLEMMY
QDELRGMPGK KSYPVNAAGK IVGNGTLEKP EKGKNLRLTI DTNVQLAAQQ AIMDQLKWLH
NPPSAYARYA APYARSGYAV AMEVDTGKVV AMASMPDYDT NLWTGGMDPK IYPQVKYFVN
NGTIRNSPPN FPDDQQKRHP SSILYLGSTI KPLSILIGLK EGLITPGSYY NDNAPFVYGK
DNSTVRNSDN HYTGMISPTR AIEVSSNTYM SAKIGIPFYN KYQRKSGEAW EKQLAEFGLG
VTTGSGLPWE YDGMSEIDAA AKTSSYQSAM VFASWGQNGK YTTLQLTQFA ATLGSRGKRV
KPQFVEEILD SDGKVVKGYE PEILNQVDLP KTYWDTVING MKSGAEGIDK LPYPVARKTG
TSTQQVSGGT VDNAVFISFA PAQNPKLAIA VVVPEGGYGR YGASPIAAKI YEAYDQYVGG
LSTPKK
//
