ID F5XHY5_MICPN Unreviewed; 614 AA.
AC F5XHY5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Putative modular polyketide synthase {ECO:0000313|EMBL:BAK33280.1};
GN OrderedLocusNames=MLP_02660 {ECO:0000313|EMBL:BAK33280.1};
OS Microlunatus phosphovorus (strain ATCC 700054 / DSM 10555 / JCM 9379 / NBRC
OS 101784 / NCIMB 13414 / VKM Ac-1990 / NM-1).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Microlunatus.
OX NCBI_TaxID=1032480 {ECO:0000313|EMBL:BAK33280.1, ECO:0000313|Proteomes:UP000007947};
RN [1] {ECO:0000313|EMBL:BAK33280.1, ECO:0000313|Proteomes:UP000007947}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700054 / DSM 10555 / JCM 9379 / NBRC 101784 / NCIMB 13414
RC / VKM Ac-1990 / NM-1 {ECO:0000313|Proteomes:UP000007947};
RA Hosoyama A., Sasaki K., Harada T., Igarashi R., Kawakoshi A., Sasagawa M.,
RA Fukada J., Nakamura S., Katano Y., Hanada S., Kamagata Y., Nakamura N.,
RA Yamazaki S., Fujita N.;
RT "Whole genome sequence of Microlunatus phosphovorus NM-1.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|RuleBase:RU003694}.
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DR EMBL; AP012204; BAK33280.1; -; Genomic_DNA.
DR AlphaFoldDB; F5XHY5; -.
DR STRING; 1032480.MLP_02660; -.
DR KEGG; mph:MLP_02660; -.
DR eggNOG; COG3321; Bacteria.
DR HOGENOM; CLU_000022_16_2_11; -.
DR OrthoDB; 9808669at2; -.
DR Proteomes; UP000007947; Chromosome.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007947};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 2..428
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 614 AA; 66987 MW; 4A44C56BD9D3F70D CRC64;
MTTPIAITGL ALRLPGATTQ DEFWQLLVDG VDRTAVVSER RRELARAPHW RDTIGEVDDI
EYFDAGFFGI EADEARFMDP QHRMVMELSY EAMCDAGLLE TRRQAGPRAA DRRYAVHMAI
ASNSYYPLVC RYLDEHGTAD VHPRTVMNVI NSALAARVSH QYDLTGPVMA VDTACSSFLT
SLTQAADAIR HQDCDGAVVG GANLFSAAYN AQLCTIGGIT TSHPYTRVFD EKADGTLLGE
GAVVCVLERE DIALRRNRRI YGRIRGYAIN NDGSSLNIMA PNPRGQANVI RDCYADGLDH
TRVSYVEAHG TGTRIGDPIE LNALSKVFRK SDFGDTAVGI GSVKSNIGHL LGAAGGAGLA
KLLLCLQHEQ LVPNLHLETV NPLLQLEDTP FRVITEPTLW PRVADRPRQG AITSLGLGGT
NVHVVIEEGD PERRGTELSC PVLCLSAQDE DALHRMLDDL SAQLTRRDVD PYNLAMTLAR
FRPAYDWRAT VRFDPASRAL CEVGVTHVDR PVRRVLLRPT LTASAGEERL RAALASPLLV
SDAEPGRSEL AVSLGSGDHD PRTVVLDPGW LPLETAAALF AAGAAVDWEH FFPAGTGTVL
TLMPYPYSKK PHWL
//
