ID F5XK86_MICPN Unreviewed; 460 AA.
AC F5XK86;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Putative mannitol dehydrogenase {ECO:0000313|EMBL:BAK33582.1};
DE EC=1.1.1.67 {ECO:0000313|EMBL:BAK33582.1};
GN OrderedLocusNames=MLP_05680 {ECO:0000313|EMBL:BAK33582.1};
OS Microlunatus phosphovorus (strain ATCC 700054 / DSM 10555 / JCM 9379 / NBRC
OS 101784 / NCIMB 13414 / VKM Ac-1990 / NM-1).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Microlunatus.
OX NCBI_TaxID=1032480 {ECO:0000313|EMBL:BAK33582.1, ECO:0000313|Proteomes:UP000007947};
RN [1] {ECO:0000313|EMBL:BAK33582.1, ECO:0000313|Proteomes:UP000007947}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700054 / DSM 10555 / JCM 9379 / NBRC 101784 / NCIMB 13414
RC / VKM Ac-1990 / NM-1 {ECO:0000313|Proteomes:UP000007947};
RA Hosoyama A., Sasaki K., Harada T., Igarashi R., Kawakoshi A., Sasagawa M.,
RA Fukada J., Nakamura S., Katano Y., Hanada S., Kamagata Y., Nakamura N.,
RA Yamazaki S., Fujita N.;
RT "Whole genome sequence of Microlunatus phosphovorus NM-1.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AP012204; BAK33582.1; -; Genomic_DNA.
DR RefSeq; WP_013861471.1; NC_015635.1.
DR AlphaFoldDB; F5XK86; -.
DR STRING; 1032480.MLP_05680; -.
DR KEGG; mph:MLP_05680; -.
DR eggNOG; COG0246; Bacteria.
DR HOGENOM; CLU_027324_0_0_11; -.
DR Proteomes; UP000007947; Chromosome.
DR GO; GO:0050086; F:mannitol 2-dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0019594; P:mannitol metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR000669; Mannitol_DH.
DR InterPro; IPR013118; Mannitol_DH_C.
DR InterPro; IPR023027; Mannitol_DH_CS.
DR InterPro; IPR013131; Mannitol_DH_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43362:SF1; MANNITOL DEHYDROGENASE 2-RELATED; 1.
DR PANTHER; PTHR43362; MANNITOL DEHYDROGENASE DSF1-RELATED; 1.
DR Pfam; PF01232; Mannitol_dh; 1.
DR Pfam; PF08125; Mannitol_dh_C; 1.
DR PRINTS; PR00084; MTLDHDRGNASE.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00974; MANNITOL_DHGENASE; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:BAK33582.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007947}.
FT DOMAIN 22..182
FT /note="Mannitol dehydrogenase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01232"
FT DOMAIN 210..405
FT /note="Mannitol dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08125"
SQ SEQUENCE 460 AA; 48766 MW; 469D1A1E49CF2BE5 CRC64;
MTTALPRLSR SLPAAPPAAP IKIVHLGLGN FHRAHQAWYT AHAPDASAWG IAAFTGRRPD
AALALAPQDG LYTLIVKGPE GDRLELLGAV SAVHAAGDHD TYLDYLRRSE VSLVTLTMTE
AAYLSDGVGG LRRTPEVEQD LASLRSDASA AVVTLPARLV AGLLARRAAG AGPITVLSCD
NLPHNGSATA GVVTALAAGV DPSLVDWISD HVDFASSMVD RITPATTDGD RELVAERCSY
LDAAPVPTEP FSEWVIAGSF PAGRPQWEAA GAQLVDDVTP YEQRKLWLLN GSHSLLAYAG
SVRGHTYIDE AIADPVCRGW VQALWDETVP HLPLPAEDLD SYRSALLERY ANPRIRHRLA
QIAADGSTKI AVRTLPVLRA ERAAGRVPVG CATAIAGWIQ HLRGAGVPVN DAGAEPYLGL
VSLPDEAAVR GVLELLDSGR GSDDELVAAV LSRLHERHHS
//
