ID F5XWZ0_RAMTT Unreviewed; 1915 AA.
AC F5XWZ0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN Name=uvrA2 {ECO:0000313|EMBL:AEG91751.1};
GN OrderedLocusNames=Rta_06730 {ECO:0000313|EMBL:AEG91751.1};
OS Ramlibacter tataouinensis (strain ATCC BAA-407 / DSM 14655 / LMG 21543 /
OS TTB310).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Ramlibacter.
OX NCBI_TaxID=365046 {ECO:0000313|EMBL:AEG91751.1, ECO:0000313|Proteomes:UP000008385};
RN [1] {ECO:0000313|Proteomes:UP000008385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-407 / DSM 14655 / LMG 21543 / TTB310
RC {ECO:0000313|Proteomes:UP000008385};
RA Barakat M., Ortet P., De Luca G., Jourlin-Castelli C., Ansaldi M., Py B.,
RA Fichant G., Coutinho P., Voulhoux R., Bastien O., Roy S., Marechal E.,
RA Henrissat B., Quentin Y., Noirot P., Filloux A., Mejean V., DuBow M.,
RA Barras F., Heulin T.;
RT "Genome of the cyst-dividing bacterium Ramlibacter tataouinensis.";
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEG91751.1, ECO:0000313|Proteomes:UP000008385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-407 / DSM 14655 / LMG 21543 / TTB310
RC {ECO:0000313|Proteomes:UP000008385};
RX PubMed=21912644; DOI=10.1371/journal.pone.0023784;
RA De Luca G., Barakat M., Ortet P., Fochesato S., Jourlin-Castelli C.,
RA Ansaldi M., Py B., Fichant G., Coutinho P.M., Voulhoux R., Bastien O.,
RA Marechal E., Henrissat B., Quentin Y., Noirot P., Filloux A., Mejean V.,
RA Dubow M.S., Barras F., Barbe V., Weissenbach J., Mihalcescu I.,
RA Vermeglio A., Achouak W., Heulin T.;
RT "The Cyst-Dividing Bacterium Ramlibacter tataouinensis TTB310 Genome
RT Reveals a Well-Stocked Toolbox for Adaptation to a Desert Environment.";
RL PLoS ONE 6:E23784-E23784(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; CP000245; AEG91751.1; -; Genomic_DNA.
DR RefSeq; WP_013899984.1; NC_015677.1.
DR STRING; 365046.Rta_06730; -.
DR KEGG; rta:Rta_06730; -.
DR PATRIC; fig|365046.3.peg.690; -.
DR eggNOG; COG0178; Bacteria.
DR HOGENOM; CLU_001370_3_0_4; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000008385; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 3.30.190.20; -; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 3.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 2.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 3.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008385};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 656..948
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1029..1506
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1577..1879
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 1915 AA; 209593 MW; C4F6859A5C525EF9 CRC64;
MTQGLIRIRG ARQHNLKNLD LDLRTGELTV VTGPSGSGKS SLVFDTLYAE GQRRYVETFS
AYARQFLDRM DKPAVDRVEG VPPAIAIDQT NPVRSSRSTV GTMTELNDHL KLLFARAAEL
FDRRTARRVR HDTPETIYAQ LMERTREGDP RLVVTFPVEL PASTTPEEVE QWLAASGFTR
VQAEREVATV TGPRKVLDVV ADRFRIQGVD KARAIEAIEV ALKRGAGRMA VYADASEDGH
EVWKFSTGLH CPDSDIRYAD PIPSMFSFNS AVGACEACRG FGRVIGVDWG LVIPNDKLTL
RAGAVKTIQT PAWSEAQDDL MRHAEAAGIP RDTPWYKLTP EHQAWVINGT PTYKEGNWNK
QWYGMKRFFQ YLESKAYKMH IRVLLSKYRS YTPCETCGGA RLKPESLLWR LGSKEDADAV
LEPARRFMPV GVEWTRGQLE ALPGLSLHDL MMLPIDRLQK FFARLQPHAG DHAGEGETQA
LKLLYEEITT RLRYLVDVGI GYLTLDRQSR TLSGGEVQRI NLTTALGTSL VNTLFVLDEP
SIGLHPRDIH RITEAMKRLR DAGNTLVVVE HDPAVMLAAD RMIDMGPAPG ERGGQIVFDG
STDALRHADT LTGQYLGGRK QVGMGFKRAV TDATPRLVLE GASEHNLKNV SVEFPLQRLV
VVTGVSGSGK SSLVQDILAP ALLRHFGRAT ETPGHHERLL GADHLGDVVF VDQSPIGKTA
RSNPVSYVGA WDCIREIFAT APLARQRGYT GSKFSFNSGD GRCPTCGGSG FEHVEMQFLS
DVYLRCPDCD GKRYRPEILE IAIERQAVGA VHPRAMNVAD VLELTVSEAA ALFANDRDVI
RALQPIVDVG LEYVKLGQPV PTLSGGESQR LKLAGFLAEA AGRRSSQALA TRGTLFLFDE
PTTGLHFDDI AKLMRALRKL LDAGHSLVVI EHNLDVIRAA DWLVDLGPEG GDSGGLLVAE
GSPEEVRQHP TSHTAKALRE YDGTLGMASE RVPDFQRPRP NPPAKGAGAI QIVNAREHNL
KSMSVDIPHN KFSVVTGVSG SGKSTLAFDI LFNEGQRRYL ESLNAYARSI VQPAGRPEVD
AVYGIPPTVA IEQRLSRGGR KSTVGTTTEV WHFLRLLYVK LGVQHCVKEG AEVRPQTPDS
IAAQILRRYR GQHVGLLAPL VVNRKGVYTE LADWARPRGY THLRVDGNFL PTTGFPRIDR
FKEHTIELPV CDLDVRPENE ALLREKLAIA LEHGKGVLHL LAPLDRLRTA FSRGVATHSD
IGTVEVFSTR RACPVCSTSY PELDPRLFSY NSKHGWCPEC VGTGVKLTRE QRKAFDDTVA
ADDTKGREQT FAEPEVEDVT DEACPACRGA RLNGQARAVR FDGVGIDEIA ALSVTDVRRW
IEKLQAQGGL SAREQGIARD LIPEIRSRLE FLEEVGLGYL TLDRGAPTLS GGEAQRIRLA
AQLGSNLQGV CYVLDEPTIG LHARDNQILL NALHKLGGKG NTLVVVEHDE DTIRRADHII
DIGPSAGKRG GRVIAQGTAA QVTANPESLT GRYLLHAMKH PLRPRREVTA VEADTTFLQL
RGARLHNLQD VDVDVPLRRL VVVTGVSGSG KSTLARDVLL HNVQLAVQQR ATKAGRDADD
RGKRPAWAGC ASLDGYQAVD RVLEVDQTPI GKTPRSCPAT YIGFWDTIRR LFADTLEAKA
RGYGPGRFSF NTGASGGASG SGRCPTCEGQ GVRTIAMSFL PDVKVPCESC HGARFNPETL
AVTWRGKSIG DVLQMEVDEA VGFFASMPSI SHPLQLLKDV GLGYLTLGQP SPTLSGGEAQ
RIKLVTELSK VRDDITRRGQ KPPHTLYVLD EPTVGLHMAD VEKLIRVLHR LVDGSHSVVV
IEHDLDVIAE ADWVVDLGPE GGTAGGRIVA AAPPEEVVRL ATHTGRVLGP VLARS
//
