ID F5YV46_MYCSD Unreviewed; 527 AA.
AC F5YV46;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Fatty-acid-CoA ligase {ECO:0000313|EMBL:AEF38259.1};
GN OrderedLocusNames=JDM601_4259 {ECO:0000313|EMBL:AEF38259.1};
OS Mycolicibacter sinensis (strain JDM601) (Mycobacterium sinense).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacter.
OX NCBI_TaxID=875328 {ECO:0000313|EMBL:AEF38259.1, ECO:0000313|Proteomes:UP000009224};
RN [1] {ECO:0000313|EMBL:AEF38259.1, ECO:0000313|Proteomes:UP000009224}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JDM601 {ECO:0000313|EMBL:AEF38259.1,
RC ECO:0000313|Proteomes:UP000009224};
RX PubMed=21685274; DOI=10.1128/JB.05291-11;
RA Zhang Z.Y., Sun Z.Q., Wang Z.L., Wen Z.L., Sun Q.W., Zhu Z.Q., Song Y.Z.,
RA Zhao J.W., Wang H.H., Zhang S.L., Guo X.K.;
RT "Complete genome sequence of a novel clinical isolate, the nontuberculous
RT Mycobacterium strain JDM601.";
RL J. Bacteriol. 193:4300-4301(2011).
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DR EMBL; CP002329; AEF38259.1; -; Genomic_DNA.
DR RefSeq; WP_013831180.1; NC_015576.1.
DR AlphaFoldDB; F5YV46; -.
DR STRING; 875328.JDM601_4259; -.
DR KEGG; mjd:JDM601_4259; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_0_11; -.
DR Proteomes; UP000009224; Chromosome.
DR GO; GO:0016877; F:ligase activity, forming carbon-sulfur bonds; IEA:UniProt.
DR CDD; cd17631; FACL_FadD13-like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:AEF38259.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009224}.
FT DOMAIN 22..384
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 434..509
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 527 AA; 57457 MW; BAEB9BFDE41E23CE CRC64;
MKQLDAVLAA ARSHALGDIP RRPARKHPDK IALIDGDVTL TFADFEHLVN RATAALQDQG
FRPGDRVAIL AHNCWQYAVL AFATARAAVV LVPINFMLTA EEIAFILEHS GVSGFIVEAD
LAATAQTAMQ GSRSVRTTAA LVPPGQTLPS GWSDFAQWLQ TTSKAPQPYV ADDQLIRLMY
TSGTESRPKG AMHSTRSLMG NYISSIIAGS MESTDIEIHS LPLYHCAQLD NFLITDIYLG
ATSIILPRPE PEAVLRAIEK YGVTSYFAPP TVWISLLRSP LFDQVDLSTL CKGYYGASAM
PVEILAEIRD RLPGLRLWNF YGQTEMAPLA SALGPDEQDA HPGAAGRPVI NVETAILDEN
DAHVGSGIVG EIAHRSPHLM LGYLDDAAKT AEAFRGGWFH SGDLGYYDTH GLLHVVDRKK
DMIKTGGENV ASREVEEVLY RHAGIEEAAV FGLPHPVWVE AVVAAVVVRD GIEIAEGDVL
THCRTHLAGF KTPKRVFFVE SLPKNPSGKL LKRELRDRFS LEQPAVT
//
