ID F5YVP4_MYCSD Unreviewed; 342 AA.
AC F5YVP4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Cobalamin synthesis protein P47K {ECO:0000313|EMBL:AEF38301.1};
GN OrderedLocusNames=JDM601_4301 {ECO:0000313|EMBL:AEF38301.1};
OS Mycolicibacter sinensis (strain JDM601) (Mycobacterium sinense).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacter.
OX NCBI_TaxID=875328 {ECO:0000313|EMBL:AEF38301.1, ECO:0000313|Proteomes:UP000009224};
RN [1] {ECO:0000313|EMBL:AEF38301.1, ECO:0000313|Proteomes:UP000009224}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JDM601 {ECO:0000313|EMBL:AEF38301.1,
RC ECO:0000313|Proteomes:UP000009224};
RX PubMed=21685274; DOI=10.1128/JB.05291-11;
RA Zhang Z.Y., Sun Z.Q., Wang Z.L., Wen Z.L., Sun Q.W., Zhu Z.Q., Song Y.Z.,
RA Zhao J.W., Wang H.H., Zhang S.L., Guo X.K.;
RT "Complete genome sequence of a novel clinical isolate, the nontuberculous
RT Mycobacterium strain JDM601.";
RL J. Bacteriol. 193:4300-4301(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; CP002329; AEF38301.1; -; Genomic_DNA.
DR AlphaFoldDB; F5YVP4; -.
DR STRING; 875328.JDM601_4301; -.
DR KEGG; mjd:JDM601_4301; -.
DR eggNOG; COG0523; Bacteria.
DR HOGENOM; CLU_017452_1_1_11; -.
DR Proteomes; UP000009224; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR PANTHER; PTHR13748:SF70; PROTEIN COBW; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000009224}.
FT DOMAIN 235..319
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 342 AA; 36322 MW; E51482AF0465C46D CRC64;
MADRNLPAIP VIALTGYLGA GKTTLLNHVL RAPGARIGVV INDFGELNVD AGLVTGQVDE
PVSIAGGCIC HLPDEGGLDD ALEKLADPKL ALDAIIIEAS GVAEPADVSR VIRFSGVERI
RHGGVVDVID AAEHFDTVDT RSAPPQRYGV ASLVVVNKLD RIAEESRVEA LGRVEARVRE
LNPHAHVVGA VAGRVDPRLL YDVSDGDASG QMSFRELLLD EALGAHDEHH DHMHATSVTV
VGDGAVDPGP LIDLLEQPPR GVYRMKGTVA IGKRHYLFNV VGTSVHVMTA PVAAGASHLV
AIGTHLDTED VRARMAEALR PCSGKVAASG MRRLQRLRRY SI
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