ID F5YWA8_MYCSD Unreviewed; 142 AA.
AC F5YWA8;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Cell wall synthesis protein CwsA {ECO:0000256|HAMAP-Rule:MF_00927};
DE AltName: Full=Cell wall synthesis and cell shape protein A {ECO:0000256|HAMAP-Rule:MF_00927};
GN Name=cwsA {ECO:0000256|HAMAP-Rule:MF_00927};
GN OrderedLocusNames=JDM601_0009 {ECO:0000313|EMBL:AEF34009.1};
OS Mycolicibacter sinensis (strain JDM601) (Mycobacterium sinense).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacter.
OX NCBI_TaxID=875328 {ECO:0000313|EMBL:AEF34009.1, ECO:0000313|Proteomes:UP000009224};
RN [1] {ECO:0000313|EMBL:AEF34009.1, ECO:0000313|Proteomes:UP000009224}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JDM601 {ECO:0000313|EMBL:AEF34009.1,
RC ECO:0000313|Proteomes:UP000009224};
RX PubMed=21685274; DOI=10.1128/JB.05291-11;
RA Zhang Z.Y., Sun Z.Q., Wang Z.L., Wen Z.L., Sun Q.W., Zhu Z.Q., Song Y.Z.,
RA Zhao J.W., Wang H.H., Zhang S.L., Guo X.K.;
RT "Complete genome sequence of a novel clinical isolate, the nontuberculous
RT Mycobacterium strain JDM601.";
RL J. Bacteriol. 193:4300-4301(2011).
CC -!- FUNCTION: Required for regulated cell division, cell wall synthesis and
CC the maintenance of cell shape. {ECO:0000256|HAMAP-Rule:MF_00927}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_00927};
CC Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_00927}.
CC Note=Localizes to poles and midcell sites. {ECO:0000256|HAMAP-
CC Rule:MF_00927}.
CC -!- SIMILARITY: Belongs to the CwsA family. {ECO:0000256|HAMAP-
CC Rule:MF_00927}.
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DR EMBL; CP002329; AEF34009.1; -; Genomic_DNA.
DR RefSeq; WP_013826953.1; NC_015576.1.
DR AlphaFoldDB; F5YWA8; -.
DR STRING; 875328.JDM601_0009; -.
DR KEGG; mjd:JDM601_0009; -.
DR eggNOG; ENOG5030K8D; Bacteria.
DR HOGENOM; CLU_1914740_0_0_11; -.
DR Proteomes; UP000009224; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0042546; P:cell wall biogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00927; CwsA; 1.
DR InterPro; IPR024245; CwsA.
DR Pfam; PF10814; CwsA; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|HAMAP-Rule:MF_00927};
KW Cell division {ECO:0000256|HAMAP-Rule:MF_00927};
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_00927};
KW Cell shape {ECO:0000256|HAMAP-Rule:MF_00927};
KW Membrane {ECO:0000256|HAMAP-Rule:MF_00927};
KW Reference proteome {ECO:0000313|Proteomes:UP000009224};
KW Transmembrane {ECO:0000256|HAMAP-Rule:MF_00927};
KW Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_00927}.
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00927"
FT REGION 121..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 142 AA; 14919 MW; 6FAAA68442E39BFA CRC64;
MRLSKETQLT HRERLTRGLA HTAGGPVDVA RGAVGLGGAA VQRGAVQLRQ RYRDSRLADH
VADAADAAAR ELAAAQEVVS GLPDVLEGRS SRRRLRRSWV IAGAVGTALL VGGAVAVAIS
RASRPEEPSP RPPSVDAHPR TV
//
