ID F5YZX4_MYCSD Unreviewed; 649 AA.
AC F5YZX4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Acyl-CoA dehydrogenase {ECO:0000313|EMBL:AEF35578.1};
GN OrderedLocusNames=JDM601_1578 {ECO:0000313|EMBL:AEF35578.1};
OS Mycolicibacter sinensis (strain JDM601) (Mycobacterium sinense).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacter.
OX NCBI_TaxID=875328 {ECO:0000313|EMBL:AEF35578.1, ECO:0000313|Proteomes:UP000009224};
RN [1] {ECO:0000313|EMBL:AEF35578.1, ECO:0000313|Proteomes:UP000009224}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JDM601 {ECO:0000313|EMBL:AEF35578.1,
RC ECO:0000313|Proteomes:UP000009224};
RX PubMed=21685274; DOI=10.1128/JB.05291-11;
RA Zhang Z.Y., Sun Z.Q., Wang Z.L., Wen Z.L., Sun Q.W., Zhu Z.Q., Song Y.Z.,
RA Zhao J.W., Wang H.H., Zhang S.L., Guo X.K.;
RT "Complete genome sequence of a novel clinical isolate, the nontuberculous
RT Mycobacterium strain JDM601.";
RL J. Bacteriol. 193:4300-4301(2011).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the acyl-CoA dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009347}.
CC -!- SIMILARITY: Belongs to the acyl-CoA oxidase family.
CC {ECO:0000256|ARBA:ARBA00006288}.
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DR EMBL; CP002329; AEF35578.1; -; Genomic_DNA.
DR RefSeq; WP_013828514.1; NC_015576.1.
DR AlphaFoldDB; F5YZX4; -.
DR STRING; 875328.JDM601_1578; -.
DR KEGG; mjd:JDM601_1578; -.
DR eggNOG; COG1960; Bacteria.
DR HOGENOM; CLU_014629_4_0_11; -.
DR OrthoDB; 1144545at2; -.
DR Proteomes; UP000009224; Chromosome.
DR GO; GO:0005777; C:peroxisome; IEA:InterPro.
DR GO; GO:0003997; F:acyl-CoA oxidase activity; IEA:InterPro.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IEA:InterPro.
DR Gene3D; 1.10.540.10; Acyl-CoA dehydrogenase/oxidase, N-terminal domain; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 2.
DR InterPro; IPR006091; Acyl-CoA_Oxase/DH_mid-dom.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR012258; Acyl-CoA_oxidase.
DR InterPro; IPR002655; Acyl-CoA_oxidase_C.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009075; AcylCo_DH/oxidase_C.
DR InterPro; IPR013786; AcylCoA_DH/ox_N.
DR InterPro; IPR037069; AcylCoA_DH/ox_N_sf.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR PANTHER; PTHR10909:SF378; ACYL-COENZYME A OXIDASE-LIKE PROTEIN; 1.
DR PANTHER; PTHR10909; ELECTRON TRANSPORT OXIDOREDUCTASE; 1.
DR Pfam; PF01756; ACOX; 1.
DR Pfam; PF00441; Acyl-CoA_dh_1; 1.
DR Pfam; PF02770; Acyl-CoA_dh_M; 1.
DR Pfam; PF02771; Acyl-CoA_dh_N; 1.
DR PIRSF; PIRSF000168; Acyl-CoA_oxidase; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000009224}.
FT DOMAIN 18..123
FT /note="Acyl-CoA dehydrogenase/oxidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02771"
FT DOMAIN 129..243
FT /note="Acyl-CoA oxidase/dehydrogenase middle"
FT /evidence="ECO:0000259|Pfam:PF02770"
FT DOMAIN 277..441
FT /note="Acyl-CoA dehydrogenase/oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00441"
FT DOMAIN 501..630
FT /note="Acyl-CoA oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01756"
SQ SEQUENCE 649 AA; 71242 MW; A59F07AE4A5AAC26 CRC64;
MTISAALCDT LDGRWRAVKN RVRATLSDEK FRPHHTPNTV IARAKVAEQL RIMAGTGVAA
DSFRKEHGGT GDVGAAVSMI EMLAMSDLSL MVKAGVQWGL FGGAVENLGT ERHHRAYVQK
IIDLDLLGCF AMTETGHGSD VQALETTATY DPATEEFVID SATGTARKDY IGGAAETATI
AAVFAQLRTP GPGGEEQGHG VHCLLVPIRD SEGNDLPGVT TSDCHYKGGL PGVDNGRIVF
DHVRVPRENL LNRYADVDPD GSYRSSIESD GRRFFTMIGT LIRGRVSVGG SAGAAARVAL
DIATRYALQR RQFSAPSDDG AEHEVLIMDY LVHQRRLLPL IARSYALQFA QNELVSKCHD
LQTADDPDPE EQRELEARAA GLKAANTWHA SRAIQEAREA CGGAGYMAEN RLIALRADTD
VFTTFEGDNH VLTQLVAKQL LTAYADDIAG MSPVDWVRFA AETVSDRVLK RTAAETIIQT
FVDARQDSEE EGSLFNRGTQ LHMFTDREEY LLTSVARRLR AKSEEMSDFD AFNAVQDHVL
HAAAAHIDRV VLEAFVAGIE SCPDAAAREL LELVCDLYAL SVIEDDKAWY IEHRYLSTDR
AKAVTRGIND RCRKLRPHAE TLVDGFGIPE QLRYAEMLHP EHLAETARR
//
