ID   F5Z3M8_MYCSD            Unreviewed;       691 AA.
AC   F5Z3M8;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=VWFA domain-containing protein {ECO:0000259|SMART:SM00327};
GN   OrderedLocusNames=JDM601_1928 {ECO:0000313|EMBL:AEF35928.1};
OS   Mycolicibacter sinensis (strain JDM601) (Mycobacterium sinense).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacter.
OX   NCBI_TaxID=875328 {ECO:0000313|EMBL:AEF35928.1, ECO:0000313|Proteomes:UP000009224};
RN   [1] {ECO:0000313|EMBL:AEF35928.1, ECO:0000313|Proteomes:UP000009224}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JDM601 {ECO:0000313|EMBL:AEF35928.1,
RC   ECO:0000313|Proteomes:UP000009224};
RX   PubMed=21685274; DOI=10.1128/JB.05291-11;
RA   Zhang Z.Y., Sun Z.Q., Wang Z.L., Wen Z.L., Sun Q.W., Zhu Z.Q., Song Y.Z.,
RA   Zhao J.W., Wang H.H., Zhang S.L., Guo X.K.;
RT   "Complete genome sequence of a novel clinical isolate, the nontuberculous
RT   Mycobacterium strain JDM601.";
RL   J. Bacteriol. 193:4300-4301(2011).
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DR   EMBL; CP002329; AEF35928.1; -; Genomic_DNA.
DR   RefSeq; WP_013828860.1; NC_015576.1.
DR   AlphaFoldDB; F5Z3M8; -.
DR   STRING; 875328.JDM601_1928; -.
DR   KEGG; mjd:JDM601_1928; -.
DR   eggNOG; COG2304; Bacteria.
DR   HOGENOM; CLU_018489_0_0_11; -.
DR   OrthoDB; 5171781at2; -.
DR   Proteomes; UP000009224; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF13531; SBP_bac_11; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009224};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        129..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          501..687
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|SMART:SM00327"
FT   REGION          1..117
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..47
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        99..117
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   691 AA;  72578 MW;  4BFDF3730E629F6B CRC64;
     MGRHSFPGPD DFDDEPLDPD QDWDAAAPDP FGFGDPDDDE YVDDYQDAFY DEPIGGDAGY
     DADPAQYMRR GSGSRSEEET RYRTGPFGAP GALPSGSYPD REAERDQPRR GRRELERWRR
     HRNDAGRRGV SVGVIAALIA VIVLVGTVIL WRFFGNSLSQ RSAIAAGNCA HGDLTVAVVA
     DPSIADHVQG FADRFNKTAK PVGDRCVSVQ VKPVDSDAVV SGFIGDWPAQ LGQRPALWIP
     GSSISAARLQ ASAGQETVSD SRSLVTSPVL LAVRPQLESA LQHQNWANLP DLQTDPDGLG
     RLGLAGWGQL RLALPIGGNG DAAFLAGEAV ASGAAPKGAP ATDGTGAVHR LAGAQPHLAD
     NSLAEAMNVL LRQGDSAAAP VHAVVTTEQQ LFTRGQSLSD PASTLGSWLP PGPAPVADYP
     TVLLVGSWLS QEQVSAASEF ARFARKPDQL ADLAKAGFRV EGVAPPSSDV TGFPALPDTL
     SVGDDAMRAT LANALTTLPG ASAVTIMLDE SMTTDEGGKT RLAHVVAALD QRIKALPPSS
     VVGLWTFDGV EGHSVLTSGP LDEPVNGGTR AETLTRELDA LSSTSGGAVS FTTLRLVYNQ
     VLANYHPGQT NSVLVITAGP HTDRTLDGPG LQDFIRANTD PERPVAVNVI DFGDADRAVW
     QAVAQLSGGT YQNLRGANTP ELAGTLNTLL G
//