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Database: UniProt
Entry: F6AB28_PSEF1
LinkDB: F6AB28_PSEF1
Original site: F6AB28_PSEF1 
ID   F6AB28_PSEF1            Unreviewed;       362 AA.
AC   F6AB28;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   08-MAY-2019, entry version 45.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   OrderedLocusNames=Psefu_4434 {ECO:0000313|EMBL:AEF24386.1};
OS   Pseudomonas fulva (strain 12-X).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=743720 {ECO:0000313|EMBL:AEF24386.1, ECO:0000313|Proteomes:UP000000686};
RN   [1] {ECO:0000313|EMBL:AEF24386.1, ECO:0000313|Proteomes:UP000000686}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12-X {ECO:0000313|Proteomes:UP000000686};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Mikhailova N., Pagani I., Davenport K., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Lcollab F.I.,
RA   Woyke T.;
RT   "Complete sequence of Pseudomonas fulva 12-X.";
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; CP002727; AEF24386.1; -; Genomic_DNA.
DR   RefSeq; WP_013793508.1; NC_015556.1.
DR   STRING; 743720.Psefu_4434; -.
DR   EnsemblBacteria; AEF24386; AEF24386; Psefu_4434.
DR   GeneID; 31812188; -.
DR   KEGG; pfv:Psefu_4434; -.
DR   eggNOG; ENOG4105E99; Bacteria.
DR   eggNOG; COG0722; LUCA.
DR   KO; K01626; -.
DR   OMA; YDINTGL; -.
DR   OrthoDB; 853329at2; -.
DR   BioCyc; PFUL743720:PSEFU_RS22185-MONOMER; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000000686; Chromosome.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000686};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000686};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:AEF24386.1}.
FT   DOMAIN       58    350       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   362 AA;  38905 MW;  4239AB0CC4FA5032 CRC64;
     MSVAVNSRST AKAADLHLVA APSRRHTTPL PSAAQLREEL PLSTALARQV QQQRQSIRAI
     LDGHDPRLLV VVGPCSLHDD AAVLEYAERL TALSQRVGDR LLLVMRAYVE KPRTTVGWKG
     LVYDPALDGS GDMAEGLRRS RKLMLRLLEL GLPLASEILQ PLVAGYFDDL LGWAAIGART
     SESQVHRELV SGLEMPVGFK NGTDGSLGIA CDAMRSAAHA HQHFGVDTQG RPALVQTHGN
     PDTHLVLRGG HGAPNYDAAS VATARAELER QGIAPRIMVD CSHANSGKNP LRQPEVLSDV
     LDQRLAGDGS LRAVMIESHL LDGAQSLGGE LRYGVSITDG CLGWAGTERM LIDAAIRMRH
     LV
//
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