ID   F6B2M4_DESCC            Unreviewed;       709 AA.
AC   F6B2M4;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=Glutamate synthase (NADPH) {ECO:0000313|EMBL:AEF93853.1};
DE            EC=1.4.1.13 {ECO:0000313|EMBL:AEF93853.1};
GN   OrderedLocusNames=Desca_0979 {ECO:0000313|EMBL:AEF93853.1};
OS   Desulfotomaculum nigrificans (strain DSM 14880 / VKM B-2319 / CO-1-SRB)
OS   (Desulfotomaculum carboxydivorans).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfotomaculaceae;
OC   Desulfotomaculum.
OX   NCBI_TaxID=868595 {ECO:0000313|EMBL:AEF93853.1, ECO:0000313|Proteomes:UP000009226};
RN   [1] {ECO:0000313|Proteomes:UP000009226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14880 / VKM B-2319 / CO-1-SRB
RC   {ECO:0000313|Proteomes:UP000009226};
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Mikhailova N., Lu M., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Pagani I., Stams A., Plugge C., Muyzer G.,
RA   Kuever J., Parshina S., Ivanova A., Nazina T., Woyke T.;
RT   "Complete sequence of Desulfotomaculum carboxydivorans CO-1-SRB.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002736; AEF93853.1; -; Genomic_DNA.
DR   RefSeq; WP_013809955.1; NC_015565.1.
DR   AlphaFoldDB; F6B2M4; -.
DR   STRING; 868595.Desca_0979; -.
DR   KEGG; dca:Desca_0979; -.
DR   eggNOG; COG0493; Bacteria.
DR   eggNOG; COG3383; Bacteria.
DR   HOGENOM; CLU_000422_3_4_9; -.
DR   Proteomes; UP000009226; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0004355; F:glutamate synthase (NADPH) activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.20; -; 1.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR028261; DPD_II.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR   InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR   PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   Pfam; PF00037; Fer4; 1.
DR   Pfam; PF14691; Fer4_20; 1.
DR   Pfam; PF10589; NADH_4Fe-4S; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00469; PNDRDTASEII.
DR   SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR   SUPFAM; SSF51971; Nucleotide-binding domain; 2.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:AEF93853.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009226}.
FT   DOMAIN          615..646
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   709 AA;  76531 MW;  1DA13417B53970ED CRC64;
     MTGNDCKVKQ TANLINAFLT AENYCSVCRR HFKQILDHLA RIQTGSGSRP DLLEIRDLAS
     KVTGLCQCGG GKSVAEQVMA NLQAFRDEFI IHIENHVCPA GECPQLVLAP CQAACPAGLD
     IPNYVALVGM QQYEEALARI REDVPLPGSL GRICEHPCER ACRRGQVDKP ISICALKGLA
     YDKSNQQPGD LLAPPARKFK ERVAVIGAGP AGLSAAYFLA QRGYGVTIFE AMPEPGGMLA
     YGIPPYRLPR QVLRDEIARI KALGVEIKVN TPVSNIQALK KEGFDAIFLG TGAWQGSIPI
     ANDEEFKGVF DGVTFLRTVN QQLLQNNGTP EIDLTGKQVV VVGGGNVAID AARVSLRLGA
     EEVKIIYRRT REEMPALVEE IVDAEHEGVK FDFLVSPVGL GGQNGWVAYI ECLKNELSEP
     DASGRRKPVP IAGSAYRIAA DVVIFATGQQ PDLSILHGTG AEVARNRIVV NPLTLETSLP
     GVFAGGDAVT GPASAIKAMA AGKQAAASIH AFLRGEVPTA SIKFPVKRPS IPPRKITAEQ
     KAQASQVNFH ELYMAEKKDS FAEIMQGISE AAAMAEANRC LRCDLCIACG QCVDSCHNRI
     GAAALQLGYI KDAHGETDFA RPGDKCIGCG TCSVNCPTGA ITQEDRNGFR EMRMCGSLMS
     RLELVNCQVC GQPFATEKHL DYINSKDKQV CPACSRQVWS RNVYGRWRQ
//