ID F6B509_DESCC Unreviewed; 174 AA.
AC F6B509;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Ribosome hibernation promoting factor {ECO:0000256|HAMAP-Rule:MF_00839};
DE Short=HPF {ECO:0000256|HAMAP-Rule:MF_00839};
GN Name=hpf {ECO:0000256|HAMAP-Rule:MF_00839};
GN OrderedLocusNames=Desca_2559 {ECO:0000313|EMBL:AEF95381.1};
OS Desulfotomaculum nigrificans (strain DSM 14880 / VKM B-2319 / CO-1-SRB)
OS (Desulfotomaculum carboxydivorans).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfotomaculaceae;
OC Desulfotomaculum.
OX NCBI_TaxID=868595 {ECO:0000313|EMBL:AEF95381.1, ECO:0000313|Proteomes:UP000009226};
RN [1] {ECO:0000313|Proteomes:UP000009226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14880 / VKM B-2319 / CO-1-SRB
RC {ECO:0000313|Proteomes:UP000009226};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Lu M., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Stams A., Plugge C., Muyzer G.,
RA Kuever J., Parshina S., Ivanova A., Nazina T., Woyke T.;
RT "Complete sequence of Desulfotomaculum carboxydivorans CO-1-SRB.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for dimerization of active 70S ribosomes into 100S
CC ribosomes in stationary phase; 100S ribosomes are translationally
CC inactive and sometimes present during exponential growth.
CC {ECO:0000256|HAMAP-Rule:MF_00839}.
CC -!- SUBUNIT: Interacts with 100S ribosomes. {ECO:0000256|HAMAP-
CC Rule:MF_00839}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00839}.
CC -!- SIMILARITY: Belongs to the HPF/YfiA ribosome-associated protein family.
CC Long HPF subfamily. {ECO:0000256|HAMAP-Rule:MF_00839}.
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DR EMBL; CP002736; AEF95381.1; -; Genomic_DNA.
DR RefSeq; WP_003543771.1; NC_015565.1.
DR AlphaFoldDB; F6B509; -.
DR STRING; 868595.Desca_2559; -.
DR KEGG; dca:Desca_2559; -.
DR eggNOG; COG1544; Bacteria.
DR HOGENOM; CLU_071472_0_3_9; -.
DR Proteomes; UP000009226; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0044238; P:primary metabolic process; IEA:InterPro.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR CDD; cd00552; RaiA; 1.
DR Gene3D; 3.30.160.100; Ribosome hibernation promotion factor-like; 1.
DR Gene3D; 3.30.505.50; Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain; 1.
DR HAMAP; MF_00839; HPF; 1.
DR InterPro; IPR034694; HPF_long/plastid.
DR InterPro; IPR036567; RHF-like.
DR InterPro; IPR003489; RHF/RaiA.
DR InterPro; IPR032528; Ribosom_S30AE_C.
DR InterPro; IPR038416; Ribosom_S30AE_C_sf.
DR NCBIfam; TIGR00741; yfiA; 1.
DR PANTHER; PTHR33231; 30S RIBOSOMAL PROTEIN; 1.
DR PANTHER; PTHR33231:SF1; 30S RIBOSOMAL PROTEIN; 1.
DR Pfam; PF16321; Ribosom_S30AE_C; 1.
DR Pfam; PF02482; Ribosomal_S30AE; 1.
DR SUPFAM; SSF69754; Ribosome binding protein Y (YfiA homologue); 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00839};
KW Reference proteome {ECO:0000313|Proteomes:UP000009226};
KW Ribonucleoprotein {ECO:0000313|EMBL:AEF95381.1};
KW Ribosomal protein {ECO:0000313|EMBL:AEF95381.1};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845, ECO:0000256|HAMAP-
KW Rule:MF_00839}.
FT DOMAIN 113..168
FT /note="Sigma 54 modulation/S30EA ribosomal protein C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF16321"
SQ SEQUENCE 174 AA; 19658 MW; D77AF0280DD717C7 CRC64;
MKVQVRGKNI DVTPALRDYV EKRLGKLEKF LDNIGEAQAT LVVEGDAQKI EVTIPVNGML
LRGEEATGDM YSAIDLVVEK MERQISRYKG KINRRNGRNP AGDVAGGEKI EDETPKVLRT
KRFAIKPMPL DEAIMQMNLL GHDFFVFSNA DTEQVNVIYK RKDGNYGLIE PEFE
//
