ID F6EL24_HOYSD Unreviewed; 445 AA.
AC F6EL24;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AEF42687.1};
GN OrderedLocusNames=AS9A_4254 {ECO:0000313|EMBL:AEF42687.1};
OS Hoyosella subflava (strain DSM 45089 / JCM 17490 / NBRC 109087 / DQS3-9A1)
OS (Amycolicicoccus subflavus).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Hoyosellaceae;
OC Hoyosella.
OX NCBI_TaxID=443218 {ECO:0000313|EMBL:AEF42687.1, ECO:0000313|Proteomes:UP000009235};
RN [1] {ECO:0000313|EMBL:AEF42687.1, ECO:0000313|Proteomes:UP000009235}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45089 / DQS3-9A1 {ECO:0000313|Proteomes:UP000009235};
RX PubMed=21725023; DOI=10.1128/JB.05388-11;
RA Cai M., Chen W.M., Nie Y., Chi C.Q., Wang Y.N., Tang Y.Q., Li G.Y.,
RA Wu X.L.;
RT "Complete genome sequence of Amycolicicoccus subflavus DQS3-9A1T, an
RT actinomycete isolated from crude oil-polluted soil.";
RL J. Bacteriol. 193:4538-4539(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC ECO:0000256|PIRNR:PIRNR005353}.
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DR EMBL; CP002786; AEF42687.1; -; Genomic_DNA.
DR RefSeq; WP_013809036.1; NC_015564.1.
DR AlphaFoldDB; F6EL24; -.
DR STRING; 443218.AS9A_4254; -.
DR KEGG; asd:AS9A_4254; -.
DR eggNOG; COG2252; Bacteria.
DR HOGENOM; CLU_024508_0_1_11; -.
DR OrthoDB; 9808458at2; -.
DR Proteomes; UP000009235; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR026033; Azg-like_bact_archaea.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337:SF11; GUANINE_HYPOXANTHINE PERMEASE PBUG; 1.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PIRSF; PIRSF005353; PbuG; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW Reference proteome {ECO:0000313|Proteomes:UP000009235};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT TRANSMEM 32..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 445 AA; 46346 MW; 07D07A1F3412B963 CRC64;
MTSLKTAPKR VSRGADRFFH ITEQGTTFRT EVVAGTTTFL AMAYILFVNP QILGSAGMDV
PAVFVATALA AALGSLVMGL WARYPIALAP GMGLNAFFAF TVVLGMGIPW ETALAGTLVS
GVLFFILAVT GVRGAIIRAI PLNLKFATGA GIGLFIAFIG LRNAEIVVPD EATTVTLGDL
SRPETLLALF GVAVTAVFLI RGFKGGVFYG MILTAAAGMI TGLISAPDAV VGSVPSLAPT
FGVAFGNLGE LITAQMLVVV LTMLFVDFFD TSGTLIAVAN QAGFLKNGEL PRANRALMSD
SVATMGGAVL GTSTTTSYIE SSAGVSAGGR TGLTSVVTAG FFLLSLLFSP LLAVVTPEVT
APALIIVGVF MAKALGDIEW NKLEYAIPAF ATVVAMPLTY SIANGIAFGL LLYPLLMVAK
GRWRDVHPIT YALFVVVIAH FIWLV
//
