ID F6FHF3_MYCHI Unreviewed; 276 AA.
AC F6FHF3;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=peptide chain release factor N(5)-glutamine methyltransferase {ECO:0000256|ARBA:ARBA00012771};
DE EC=2.1.1.297 {ECO:0000256|ARBA:ARBA00012771};
GN OrderedLocusNames=MHF_1551 {ECO:0000313|EMBL:AEG73783.1};
OS Mycoplasma haemofelis (strain Ohio2).
OC Bacteria; Mycoplasmatota; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=859194 {ECO:0000313|EMBL:AEG73783.1, ECO:0000313|Proteomes:UP000007952};
RN [1] {ECO:0000313|EMBL:AEG73783.1, ECO:0000313|Proteomes:UP000007952}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ohio2 {ECO:0000313|EMBL:AEG73783.1,
RC ECO:0000313|Proteomes:UP000007952};
RX PubMed=21317328; DOI=10.1128/JB.00133-11;
RA Messick J.B., Santos A.P., Guimaraes A.M.;
RT "Complete genome sequences of two hemotropic Mycoplasmas, Mycoplasma
RT haemofelis strain Ohio2 and Mycoplasma suis strain Illinois.";
RL J. Bacteriol. 193:2068-2069(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Ohio2;
RA Santos A.P., Guimaraes A.M.S., SanMiguel P.J., Martin S.W., Messick J.B.;
RT "The Genome of Mycoplasma haemofelis Strain Ohio2, a pathogenic hemoplasma
RT of the cat.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-
CC methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release
CC factor] + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:42896, Rhea:RHEA-
CC COMP:10271, Rhea:RHEA-COMP:10272, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30011, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:61891; EC=2.1.1.297;
CC Evidence={ECO:0000256|ARBA:ARBA00000932};
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DR EMBL; CP002808; AEG73783.1; -; Genomic_DNA.
DR AlphaFoldDB; F6FHF3; -.
DR STRING; 859194.MHF_1551; -.
DR KEGG; mhf:MHF_1551; -.
DR eggNOG; COG2890; Bacteria.
DR HOGENOM; CLU_993298_0_0_14; -.
DR BioCyc; MHAE859194:G1GR7-1550-MONOMER; -.
DR Proteomes; UP000007952; Chromosome.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004556; HemK-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR NCBIfam; TIGR00536; hemK_fam; 1.
DR PANTHER; PTHR18895; HEMK METHYLTRANSFERASE; 1.
DR PANTHER; PTHR18895:SF74; MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE; 1.
DR Pfam; PF05175; MTS; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:AEG73783.1};
KW Transferase {ECO:0000313|EMBL:AEG73783.1}.
FT DOMAIN 93..195
FT /note="Methyltransferase small"
FT /evidence="ECO:0000259|Pfam:PF05175"
SQ SEQUENCE 276 AA; 32659 MW; 7FCAA05B8C1934AB CRC64;
MTKRVTFKQI VEKKNFQINA YKLVYFLSSK VKNINDYQKY KATKIDFDEA YFDECYEKLS
DPNNTIERIC KKVFFHKHEF ILHDDVFCPR NETELIVEYL NQEIKEDPAL KKSNYVDLCA
GTGVIGISIA LQNEGFFKKI ALVDISEEAI KNIKENCAKY NLKASVVKQD WYEYLQENGA
DVITANFPYV SKEDDMDEHI MESEPDWALF ADNDGWEHYD KVLKFIDRNK AWKLIVLECS
AYHEKKWKSI KNTYPNVKWK FLYDLNGKLR VVSLKR
//
