ID F6FPL0_ISOV2 Unreviewed; 615 AA.
AC F6FPL0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Metallophosphoesterase {ECO:0000313|EMBL:AEG44742.1};
GN OrderedLocusNames=Isova_2006 {ECO:0000313|EMBL:AEG44742.1};
OS Isoptericola variabilis (strain 225).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Promicromonosporaceae; Isoptericola.
OX NCBI_TaxID=743718 {ECO:0000313|Proteomes:UP000009236};
RN [1] {ECO:0000313|EMBL:AEG44742.1, ECO:0000313|Proteomes:UP000009236}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=225 {ECO:0000313|Proteomes:UP000009236};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Zeytun A., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Siebers A., Allgaier M., Thelen M.,
RA Hugenholtz P., Gladden J., Woyke T.;
RT "Complete sequence of Isoptericola variabilis 225.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. YfcE
CC family. {ECO:0000256|ARBA:ARBA00008950}.
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DR EMBL; CP002810; AEG44742.1; -; Genomic_DNA.
DR RefSeq; WP_013839133.1; NC_015588.1.
DR AlphaFoldDB; F6FPL0; -.
DR STRING; 743718.Isova_2006; -.
DR KEGG; iva:Isova_2006; -.
DR eggNOG; COG0420; Bacteria.
DR HOGENOM; CLU_477102_0_0_11; -.
DR Proteomes; UP000009236; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00838; MPP_superfamily; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR024654; Calcineurin-like_PHP_lpxH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR Pfam; PF12850; Metallophos_2; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009236};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 334..502
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF12850"
FT REGION 265..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 567..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..597
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 615 AA; 63520 MW; A49333945F681F17 CRC64;
MSPSQTRARR RHAPPRWVRW TLASIAALVA CVGFGVSTAT AHLSLGPHEA VYHVTSDGLV
VADLGPLGTL EIDSPLPLGL GVEVVVKEIP SDLSAVDQAT TLAALTGDLE SYLQFFSSPD
VTVGTIARAL VADAVRRTLL AAGAVVLAGA GLRLLLGPAR RRELAGRVAP RTWELTAGTL
VVALVAVTAS ASGVEAPPRG RPASEVFEGT ALEGARITGR LAGVIDTYGG QLVGLYEENQ
RFYEGARVQL VGAWKAWEIR EAVRTSREEV GQSPLRPVPP PDDDGTTPDA TPAGDDATPA
DAATDAPAAP TSPTPSPGQT TPAASPDPED LVTLLVVADL HCNTGMTPLI REVAERAGVD
VVLNAGDTTM NGTAVERVCV DSFATTVPAG ARMVVADGNH DSPITSAQEA AHGQVILDGD
VVEVAGVRIL GDRDALETRV GAGTGVAREV TPLQQSEALA EAACADEQGV DLLLVHTATV
GTPALESGCV PFQVSGHSHR RAGPEQVGLG IRYVSASTAG ATSGQPTVGP LRGTAEMTLL
RFDPEARRFV DWQLVEVRPS GEATVYDRRA VPAVEPPAEV PPDDVDGGDE DQGRGPDDED
GEPQVGTDAS ATPAP
//
