ID F6FQT4_ISOV2 Unreviewed; 401 AA.
AC F6FQT4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Beta-ketoacyl-acyl-carrier-protein synthase I {ECO:0000313|EMBL:AEG42899.1};
DE EC=2.3.1.41 {ECO:0000313|EMBL:AEG42899.1};
GN OrderedLocusNames=Isova_0085 {ECO:0000313|EMBL:AEG42899.1};
OS Isoptericola variabilis (strain 225).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Promicromonosporaceae; Isoptericola.
OX NCBI_TaxID=743718 {ECO:0000313|Proteomes:UP000009236};
RN [1] {ECO:0000313|EMBL:AEG42899.1, ECO:0000313|Proteomes:UP000009236}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=225 {ECO:0000313|Proteomes:UP000009236};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Zeytun A., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Siebers A., Allgaier M., Thelen M.,
RA Hugenholtz P., Gladden J., Woyke T.;
RT "Complete sequence of Isoptericola variabilis 225.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
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DR EMBL; CP002810; AEG42899.1; -; Genomic_DNA.
DR RefSeq; WP_013837294.1; NC_015588.1.
DR AlphaFoldDB; F6FQT4; -.
DR STRING; 743718.Isova_0085; -.
DR KEGG; iva:Isova_0085; -.
DR eggNOG; COG0304; Bacteria.
DR HOGENOM; CLU_000022_69_2_11; -.
DR Proteomes; UP000009236; Chromosome.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:AEG42899.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009236};
KW Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:AEG42899.1}.
FT DOMAIN 1..400
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 401 AA; 41066 MW; 58BA63277F42FE98 CRC64;
MRRAVVTGLG AVTPLGRTAD ETWKGLAEGI GAVTALEEDW ARELPVRIAA RVDDAFAETL
EVRELRRLDR AEQLTLVAGR EAWASAGAPD VDPTRLAVAV GTANGGIGTT LVQHEVLTTQ
GHRRVSPHAV TMVMANGPAA WLSMDLGAKA GARAPVSACA AGVEAILTGR ELIRSDQADV
VVCGGVEASI VDLCISAFAR SRAMSTRNDE PERASRPFDA ERDGFVMGEG AALLVLEAEE
HAAARGADVL GAVDGAALTS DAHDIVGGEP QNQARTIGLA LRSAELAPAH VGLVHAHATS
TPLGDVNEAD ALRSVFGDPP PVTATKASTG HLLGASGALG ALAALLSLHH GVVPPTLNLE
TPDPAIDLDV VTSARPTAAE HALVNAFGFG GHSAALVLSR S
//
