ID   F6FVT1_ISOV2            Unreviewed;      1013 AA.
AC   F6FVT1;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   27-MAR-2024, entry version 67.
DE   SubName: Full=Transcriptional regulator, LuxR family {ECO:0000313|EMBL:AEG45582.1};
GN   OrderedLocusNames=Isova_2897 {ECO:0000313|EMBL:AEG45582.1};
OS   Isoptericola variabilis (strain 225).
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC   Promicromonosporaceae; Isoptericola.
OX   NCBI_TaxID=743718 {ECO:0000313|Proteomes:UP000009236};
RN   [1] {ECO:0000313|EMBL:AEG45582.1, ECO:0000313|Proteomes:UP000009236}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=225 {ECO:0000313|Proteomes:UP000009236};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Mikhailova N., Zeytun A., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Pagani I., Siebers A., Allgaier M., Thelen M.,
RA   Hugenholtz P., Gladden J., Woyke T.;
RT   "Complete sequence of Isoptericola variabilis 225.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002810; AEG45582.1; -; Genomic_DNA.
DR   AlphaFoldDB; F6FVT1; -.
DR   STRING; 743718.Isova_2897; -.
DR   KEGG; iva:Isova_2897; -.
DR   eggNOG; COG2909; Bacteria.
DR   HOGENOM; CLU_006850_0_2_11; -.
DR   Proteomes; UP000009236; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   CDD; cd01983; SIMIBI; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009236}.
FT   DOMAIN          944..1009
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50043"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1013 AA;  108997 MW;  D2F3C18007EE46AF CRC64;
     MTTSAQHALG EMPSAAVGGG WDDRDVRRSS RIPLVARQAQ VAGFRRALER AAAGEPGVLL
     VGGDAGVGKT RLVSHLAATA EQAGARVVVA HCVDLGEVGI PYLPFSEALA QLRRPAAHAT
     SPARAGSDDV AAGVAQLVAQ RPALARLVDP AGPGASEAGE HAERLQLFDG IASSLAAAGR
     PGAPLVLVIE DVHWADPSTR DVLRFLVTRL RSEHLLLVVT YRSDDVDRRH PLRPLLAELH
     RQERVEHVEL DPFTADELRE FTTALSGAPL PERDFAEVLR RSEGNAFFAE ELVSAGLESG
     HLPWSLADVL HARMQRLEPA VQQLVRLASV AGRQVREDLL RAAAGRMRGL EDPVVLATAL
     QEAVAHQVLG VEGTHLAFRH ALLAEALYLD LLPGERVAMH RAYLAALLAE PGLGSAAERA
     HHAQQAHDLP TALVASAEAA ERARDLLAPT EELRHLEQVL SLWEVVPDAE ARLGRDRVAV
     ALRAAGAAAR SGQRTRAEQL ARRAVDALRD DPQRQARVRH NLARYLLDVE DPRGAAEQTV
     LALQVLPAEP TADLAWTLAV RGRVELIRDA DDEARAYLEQ AVDVARAAGA PGPEADALAS
     LAILEVGDPA TAARLLETAL ARAVDAESLS TELRCWYNLA TTWFYAGHVD EAEDVLRRGL
     DRARETGMSW SSYGSAMHQL TEIVRYFRGH LDEPDPLDGV PSSEAVFLAG AHLYAAVARG
     DEDAIERAEA MRDRWDVDGF IALTSGGCRV DALTWAGRYD EAVELAHEVA DHLGAVWSTY
     FLGRIWISAL ALAALAGAAE EAAAAPDAPE QAERRAHGDA LLAVAQETAR RGRPRGGSLG
     PEGRAWLRRA EAEHARLVAA TGGEPADPAL WEATVREFGF GYRYEVARSR FRWAQALRAA
     GDRNAAELEA AEALREARDM GARPLADALL AWARRARLPL PGVRREATSA LTEREEEVLA
     LVAQGLSNRQ IGERLYISTK TVSVHVSNLL AKLGVSGRAE AVAVATRRGL LEV
//