ID F6FX66_ISOV2 Unreviewed; 356 AA.
AC F6FX66;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:AEG43569.1};
GN OrderedLocusNames=Isova_0783 {ECO:0000313|EMBL:AEG43569.1};
OS Isoptericola variabilis (strain 225).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Promicromonosporaceae; Isoptericola.
OX NCBI_TaxID=743718 {ECO:0000313|Proteomes:UP000009236};
RN [1] {ECO:0000313|EMBL:AEG43569.1, ECO:0000313|Proteomes:UP000009236}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=225 {ECO:0000313|Proteomes:UP000009236};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Zeytun A., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Siebers A., Allgaier M., Thelen M.,
RA Hugenholtz P., Gladden J., Woyke T.;
RT "Complete sequence of Isoptericola variabilis 225.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002810; AEG43569.1; -; Genomic_DNA.
DR RefSeq; WP_013837961.1; NC_015588.1.
DR AlphaFoldDB; F6FX66; -.
DR STRING; 743718.Isova_0783; -.
DR KEGG; iva:Isova_0783; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_1_11; -.
DR Proteomes; UP000009236; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01574; PBP1_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000009236};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 17..71
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 356 AA; 36619 MW; C24CD7FE72A8DF7A CRC64;
MSGPAAPGRA AARVRRPSMA DVAAVAGVSH QTVSRVLNAH PSVRGETRER VLQAIESLGY
RRNSAARALA TARSATLGVV TTGSALFGPT STLVAVEGAA RDEGYFVSVA TLRTYDAAAM
HEALEHFMAQ GVEGIVVIAP QDDVAAAVES FRAPVPVVVV AALEDAESAP GGPATLSLAV
DQRSGARLAT DHLLDLGHHD VVHVAGPQDW FDARERAAGW REALEARGVT PTRPRVCSWS
ADDGYAAGRD LAEAVGAGEG PTAVLAGNDQ LALGILRALW ERGLDVPGDV SVVGFDDVAG
AAYFVPPLTT VRQPFARLGA RAVAMVLAAL AGGDVPPERI APELVVRSST GAPCSG
//
