ID F6GVU9_VITVI Unreviewed; 5063 AA.
AC F6GVU9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 24-JAN-2024, entry version 67.
DE RecName: Full=Auxin transport protein BIG {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=VIT_14s0083g00960 {ECO:0000313|EMBL:CCB44084.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB44084.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SIMILARITY: Belongs to the UBR4 family.
CC {ECO:0000256|ARBA:ARBA00009970}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FN594955; CCB44084.1; -; Genomic_DNA.
DR STRING; 29760.F6GVU9; -.
DR PaxDb; 29760-VIT_14s0083g00960-t01; -.
DR eggNOG; KOG1776; Eukaryota.
DR HOGENOM; CLU_223526_0_0_1; -.
DR InParanoid; F6GVU9; -.
DR Proteomes; UP000009183; Chromosome 14.
DR ExpressionAtlas; F6GVU9; baseline and differential.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009926; P:auxin polar transport; IBA:GO_Central.
DR CDD; cd19681; UBR-box_BIG_like; 1.
DR CDD; cd02249; ZZ; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR025704; E3_Ub_ligase_UBR4_C.
DR InterPro; IPR045189; UBR4-like.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR003126; Znf_UBR.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR21725; E3 UBIQUITIN-PROTEIN LIGASE UBR4; 1.
DR PANTHER; PTHR21725:SF1; E3 UBIQUITIN-PROTEIN LIGASE UBR4; 1.
DR Pfam; PF13764; E3_UbLigase_R4; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00396; ZnF_UBR1; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51157; ZF_UBR; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 1518..1589
FT /note="UBR-type"
FT /evidence="ECO:0000259|PROSITE:PS51157"
FT DOMAIN 2556..2614
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT ZN_FING 1518..1589
FT /note="UBR-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00508"
FT REGION 1432..1511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2781..2803
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3089..3126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3763..3813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4903..4938
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1457..1480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1482..1505
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3106..3124
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3775..3798
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5063 AA; 561930 MW; 9540FE417089FF40 CRC64;
MASDFTKLVE ALFEDKSSPS DLCQRLRSDD SIKAGLQAFY SILKNAVVST DPKLSLLSWD
NSQIQSEKVD FKRTKAWKPT NNVVQLLEIA LVAGVDKEPD PSQPCSVYTL VDLLPLLTVK
SGDIELENHI KCNPQGVSCS RGEKPVDRLL MTLASECMQP DSQMQRFTGP NFHQDLNKLV
SLSQHWAVLH VGCIQRLIRL CKELLILPDM FDDEKTAGIN FRKRLSFGLR ILKLLGSLTR
DIPYVEYDPA LLQAVASCAD VLPSLFKPGF EFANSHAPVE SSFENLVLLL LEEFLHLVRV
IFWTSSVFQN IQACIIASVL DNLDSDVWRY NKSAANPKPP LAYFPRSVIY ILKLIVEVKK
QTYQAFDVQD DFQIDSPSCR LHSEKISLLK KYTVEELLKK IFPSSNQWVD NLMDLVFFLH
SEGVKLRPKL ERSFSSCAKA SCNSETENAV CHEDEALFGD LFSEGGRSVG STDGCDQAPA
SVNPTSNYCN MPIQAASEVL GFLKDCAFSP EWHTSVYEDG CKKLSGKHID ILLSILNCQG
CYSEDRISDN LTGLQEQRKT GHVHELCFEL LHNLLTRHAL SDSLEEYLFG QILNVDSGCF
IYNDLTLTLL AHSLICRVGL AGSQLRSKIY RGYIDFIVEK TKALYSKCPS LKELFGTLPS
VFHIEILLMA FHLSSEGEKA TLANLIFSSL RTIDAPADGF NSTQLSCWAI LVSRLILVLR
HMIFYPRACP SSLLLDLRSK LREAPLAGSN PSVNPSDNLS SWASIAVENI MGAWIKEDPF
LSSLVNQLSD VASLPASLCR DDLAIQSLCL HWDDICASFY WILGFWKGKK ATTVEDLILE
RYIFILCWDI PTMGSALDHP LPLWNDLQTL DLSDVKYFFH FSHSFLGHSG VIGEGISFLD
VVIGVLQHLH AVHITDDIED LGWDFLRNGM WLSLVLSLLQ TGIGEYCLKN SVPGMGPISP
EYASSDNEYL TLAEGLISSL LEAGQVAKVS RILSSFLNRY LQAYQKAFLS TIDNGQYHGD
RFSPLLLLKH TGVDKCMQDG LLEKSGINPC HLESVYGLLS KLDQMVKKRA SGFLSKVFWE
CILHGFPSHL QASSGILLSC ILSIRGIICI LEGLLKIKDA RGNILMETEV LQEILDSVMT
IKCDRIFESL HGNCEAIYHS LSAGMEGSDF SYLFQMKQME GFLRDINAGE VSDGSIHECI
VTKAIDMMDI LRKDPSLAVI FKFYVSMVDV SEKVEELYGL QRGDLLVLVD SLDNCYSESV
NVKVLNFFVD LLSGDLCPDL KQKIQTKFLS MDLLCLSKWL EKRLVGCAVD ASEGVSCAKA
SSTTLRESTM NFILCLVSPH DMQSKELHSH LFEAMLISLD TAFILFDIHT AKSYFHFIVQ
LSRGESLMKP LLKRTVALME KLAGDEGLLQ GLKFLFGFLG TVLSDCRSNK STLEKSPGKP
FSSGSIGVGP VASRPVGSRK NSETLVLSAN QETGSASLEC DATSVDEDED DGTSDGEVAS
MDKDEEDDSN SERALASKVC TFTSSGSNFM EQHWYFCYTC DLTVSKGCCS VCAKVCHRDH
RVVYSRSSRF FCDCGAGGVR GSNCQCLKPR KFTGSNSAPV RGSVNFQSFL PFTEDGDQLP
DSDSDLDEDG CTDVDNSVSL SISRELQDGM PVLLEELDVE GQVLELCSSL LPSIVSKRDS
NLSQDKKIIL GKDKVLSYGV DILQLKKAYK SGSLDLKIKA DYSNAKELKS HLSSGSLVKS
LLSVSIRGRL AVGEGDKVAI FDVGHLIGQA TIAPVTADKT NVKPLSKNVV RFEIVHLVFN
PVVENYLAVA GFEDCQVLTL SPRGEVTDRL AIELALQGAY IRRIDWVPGS QVQLMVVTNR
FVKIYDLSQD NISPMHYFTL SDDMIVDATL LVASQGRVFL IVLSELGSLY RLELSLEGNV
GAKPLKEIIH IQDRNIQAKG SSVYFSSTYK LLFISYQDGT TFIGRLNPNA TSLTEISAVY
EDEQDGKLRP AGLHRWKELL VGSGLFVCFS SVKPNVALAI SMGSNELFAQ NMRHAVGSTS
PLVGITAYKP LSKDKIHCLV LHDDGSLQIY SHVPMGVDAG ASVTLDKVKR LGSDILNNKA
YAGTNPEFPL DFFEKTVCIT ADVKLGGDAV RNGDSEGAKH SLVSEDGFLE SPSPAGFKIT
VANSNPDIVM VGFRVHVGNT SASHIPSDIT IFQRVIKLDD GMRSWYDIPF TVAESLLADE
EFTVSVGSTF NGSALPRIDS LEVYGRAKDE FGWKEKMDAI LDREARVLGC NSWVAGSGKK
CRSMQSAPIQ EQVVADGLKL LSRLYSVCRP QGCSKVEEVK SELNKLKCKL LLETIFESDR
EPLLQAAACC VLQAVFPRRE IYYQVKDTMR LLGVVKSTSV LSSRLGVGGT TAGWIIEEFT
AQMRAVSKIA LHRRSNLATF LEINGSEVVD GLMQVLWGIL DIEQPDTQTM NNIVVSSVEL
IYCYAECLAL HGRDTGGRSV APAVVLFKKL LFSPNEAVQT SSSLAISSRL LQVPFPKQTM
LPTDDVVEST VSTSVTADAA GGNTQVMIEE DSITSSVQYC CDGCSTVPIL RRRWHCNVCP
DFDLCEACYE LDADRLPPPH SRDHLMSAIP IEVETLGGDG SEIHFSTDDL SESSLLPVTT
DVTVQNSTPA IHVLEPNESG EFSASVIDPV SISASKRAVN SLLLSELLEQ LKGWMKTTSG
LQAIPVMQLF YRLSSAVGGP FIDSSRPESL DLEKLIKWFL DEINLSKPFV AKTRSPFGEV
AILVFMFFTL MLRNWHQPGS DGSIPKSSGG SDMQDKSNIQ IPPSTSIVAP SSLDDQEKHD
SASQLLQACS SLRQQAFVNY LMDILQQLVH VFKSPNVNFE AAHGANPGLG CGALLTVRRE
LPAGNFSPFF SDSYAKAHRM DIFMDYHRLL LENAFRLVYG LVRPEKQDKT GEKEKVYKMS
SGKDLKLDGY QDVLCSYINN SHTTFVRRYA RRLFLHLCGS KTHYYSVRDS WQFSSEAKKL
YKHVNKSGGF QNPVPYERSV KIVKCLSTMA EVAAARPRNW QKYCLRNGDV LPYLMNGIFY
FGEESVVQTL KLLSLAFYTG KDISHSLPKA EAGDAGTSSN KSGTVSLDSK KKKKGEDGSE
SASEKSYLDM EPAVDIFTEK GGDVLRQFIN SFLLEWNSSS VRIEAKCVLY GVWHHGKQSF
KETMLVALLQ KVECLPMYGQ NIVEYTELVT WLLGKVPDTS SKPQSTELVD RCLTTDVVRC
IFETLHSQNE LLANHPNSRI YNTLSGLVEF DGYYLESEPC VACSSPEVPY SRMKLESLKS
ETKFTDNRII VKCTGSYTIQ TVTMNVHDAR KSKSVKVLNL YYNNRPVADL SELKNNWALW
KRAKSCHLAF NQTELKVDFP IPITACNFMI ELDSFYENLQ ALSLEPLQCP RCSRPVTDKH
GICSNCHENA YQCRQCRNIN YENLDSFLCN ECGYSKYGRF EFNFMAKPSF TFDSMENDDD
MKRGLTAIEA ESENAHRRYQ QLLGFKKPLL KIVSSIGENE MDSQQKDSVQ QMMVSLPGPS
CKINRKIALL GVLYGEKCKA AFDSVSKSVQ TLQGLRRVLM NYLHQKHSDN AVASSRFVVS
RSPNSCYGCA TTFVAQCLEI LQVLSKHPNS KKQLVAASIL SELFENNIHQ GPKTARIQAR
AVLCAFSEGD ANAVSELNSL IQKKVMYCLE HHRSMDIALA SREELLLLSE VCSLADEFWE
SRLRVVFQLL FSSIKLGAKH PAIAEHVILP CLRIISQACT PPKPDTVDKE QGLGKSTPLL
QSKDENNSNS SGSVSGHGGG SKSVAELSEK NWDGSQKTQD IQLLSYSEWE KGASYLDFVR
RQYKVSQAVK SSGQRPRPQR YDYLALKYAL RWKRNACKTS KGELSAFELG SWVTELVLSA
CSQSIRSEMC MLISLLCAQS PARRFRLLNL LMALLPATLS AGESAAEYFE LLFKMIDSED
ARLFLTVRGC LTKICKLISQ EVGNIESLER SLHIDISQGF ILHKLIELLG KFLEVPNIRS
RFMRDNLLSE ILEALIVIRG LIVQKTKLIS DCNRLLKDLL DGLLLESSEN KRQFIRACIC
GLQIHGEERK GRTSLFILEQ LCNLICPSKP ESVYLLVLNK AHTQEEFIRG SMTKNPYSSA
EIGPLMRDVK NKICHQLDLL GLLEDDYGME LLVAGNIISL DLSIAQVYEQ VWKKSNSQSS
NTISGATLLS SNATTSARDC PPMTVTYRLQ GLDGEATEPM IKELEEDREE SQDPEVEFAI
AGAVQEYGGL EIILGMIQRL RDDLKSNQEQ LVAVLNLLMH CCKIRENRRA LLRLGALGVL
LETARCAFSV DAMEPAEGIL LIVESLTLEA NESDNISITQ NALTVSSEVA GAGDQAKKIV
LMFLERLCHS SGLKKSNKQQ RNTEMVARIL PYLTYGEPAA MEALIHHFEP YLQDWGEFDR
LQKQQQDNPK DEDIARQAAK QKFALENFVR VSESLKTSSC GERLKDIILE KGITGVAVRH
LTDSFAVAGQ AGFKSSAEWA SGLKLPSVPL ILSMLRGLSM GHLATQRCID EGGILSLLHA
LEGVTGENEI GARAENLLDT LSDKEGKGDG FLEEKVCKLR HATRDEMRRR ALRRREELLQ
GLGMRQELAS DGGERIVVTR PLLEGLEDVE EEEDGLACMV CREGYSLRPT DMLGVYSYSK
RVNLGVTSGS ARAEYVYTTV SFFNIIHFQC HQEAKRADAA LKNPKKEWEG AALRNNESYC
NSLFPVRGPS VPITQYIRYV DQYWDNLNAL GRADGPRLRL LTYDIVLMLA RFATGASFSL
ESRGGGRESN SRFLLFMIQM ARHLFDQGNI TQRAMAKTIT TYLTSSSSDS KPSTPGMQPS
IGTEETFQFM MVNSLLSESY DSWLQHRRAF LQRGIYHAYM QHTHGRSTSR ASSNPTAVIR
SESGSSSGSG STTTEAGSGD DLLAIVRPML VYTGLIEQLQ RFFKVKKSAA NVSSVKAEGR
STEIEGEENK NLEGWEMVMK ERLLNVREMV GFSKELLSWL DEVTAATDLQ EAFDIIGVLS
DVLAGGLTQC EDFVHAAINA GKS
//
