ID F6GYI7_VITVI Unreviewed; 869 AA.
AC F6GYI7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN OrderedLocusNames=VIT_09s0054g01520 {ECO:0000313|EMBL:CCB45023.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB45023.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
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DR EMBL; FN594972; CCB45023.1; -; Genomic_DNA.
DR AlphaFoldDB; F6GYI7; -.
DR STRING; 29760.F6GYI7; -.
DR PaxDb; 29760-VIT_09s0054g01520-t01; -.
DR eggNOG; KOG0497; Eukaryota.
DR HOGENOM; CLU_009074_2_0_1; -.
DR InParanoid; F6GYI7; -.
DR Proteomes; UP000009183; Chromosome 9.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0042300; F:beta-amyrin synthase activity; IBA:GO_Central.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IBA:GO_Central.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 3.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF58; BETA-AMYRIN SYNTHASE-RELATED; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 3.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|RuleBase:RU362003};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 188..461
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 517..850
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 869 AA; 99664 MW; 42003CABA84393B1 CRC64;
MACVEKTAGS QQWDTSLAIQ ALTACNLTDE IGATLMKGHD FIKKSQVRDN PSGDFRSMYR
YIFKGSWTFL DRDHGWQVSN CTTKSLKKMW RLKVADGGND PYIYSTNNFV GRQIWEFDPD
YGTPEERAEV EAARENFWKN RFQVKPSSDL LWRMQFLREK NFKQTIPQVK VGDGEEITYE
TATAAVRRGA HFFSALQASD GHWPAENAGA LYFLPPLVMC LYITGHLETV FPREYRKEIL
RYLYCHQNED GGWGLHIEGH STMFCTTLSY ICMRILGEGR DGGRDNACAR GRKWILDRGG
VTSIPSWGKT WLSIFGLFDW SGSNPMPPEF WLFPSRLPII QVTHEYLKIQ PGDAKMWCYC
RLVYMPMSYL YGKRFVGPIT PLVLELRKEL FLQPYNEINW KKVRHLCAKE DLYYPHPLIQ
DLMWDSLYIC TEPLLTRWPF NKLRQKALEV TMKHIHYEDE NSRYITIGCV EKVLCMLSCW
VEDPDGDYFK KHLARIPDYI WVGEDGIKMQ SFGSQEWDTG FALQALLACN MTDEIGPTLK
KGHEFVKESQ VKDNPSGDFK SMYRHISKGS WTFSDQDHGW QVSDCTAEGL KCCLLFSMMA
PEIVGTKMEP ERLFDSVNIL LSLQSKNGGI VGWEPAGASE WLELLNPTEM FEDLVIEHEY
VECTASAIQA LVLFKKLYPR HRTEEIDNFI TNATKYIEDQ QMPDGSWYGN WGVCFTYGSW
FALGGLAAAG RTYHNCLAIG SAVEFLLKSQ RDDGGWGESY ISCQEKKHTP LKGNKSNLVQ
TGWALMGLLS SGQAERDPTP LHRAAKLLIN SQMEDGDFPQ QEITGAFLKN CMSHYADYRN
IFPLWALAEY VSQCHRLKSG CIAMPKKHL
//
