ID F6HB92_VITVI Unreviewed; 381 AA.
AC F6HB92;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 24-JAN-2024, entry version 66.
DE RecName: Full=uroporphyrinogen-III C-methyltransferase {ECO:0000256|ARBA:ARBA00012162};
DE EC=2.1.1.107 {ECO:0000256|ARBA:ARBA00012162};
GN OrderedLocusNames=VIT_13s0064g01470 {ECO:0000313|EMBL:CCB49476.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB49476.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|RuleBase:RU003960}.
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DR EMBL; FN595509; CCB49476.1; -; Genomic_DNA.
DR RefSeq; XP_003633580.1; XM_003633532.3.
DR AlphaFoldDB; F6HB92; -.
DR STRING; 29760.F6HB92; -.
DR PaxDb; 29760-VIT_13s0064g01470-t01; -.
DR EnsemblPlants; Vitvi13g01779_t001; Vitvi13g01779_P001; Vitvi13g01779.
DR GeneID; 100852901; -.
DR Gramene; Vitvi13g01779_t001; Vitvi13g01779_P001; Vitvi13g01779.
DR KEGG; vvi:100852901; -.
DR eggNOG; KOG1527; Eukaryota.
DR HOGENOM; CLU_011276_7_4_1; -.
DR InParanoid; F6HB92; -.
DR OrthoDB; 296644at2759; -.
DR Proteomes; UP000009183; Chromosome 13.
DR ExpressionAtlas; F6HB92; baseline and differential.
DR GO; GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IBA:GO_Central.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0019354; P:siroheme biosynthetic process; IBA:GO_Central.
DR CDD; cd11642; SUMT; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR006366; CobA/CysG_C.
DR InterPro; IPR003043; Uropor_MeTrfase_CS.
DR NCBIfam; TIGR01469; cobA_cysG_Cterm; 1.
DR PANTHER; PTHR45790:SF3; S-ADENOSYL-L-METHIONINE-DEPENDENT UROPORPHYRINOGEN III METHYLTRANSFERASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR45790; SIROHEME SYNTHASE-RELATED; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
DR PROSITE; PS00839; SUMT_1; 1.
DR PROSITE; PS00840; SUMT_2; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000256|RuleBase:RU003960};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003960}.
FT DOMAIN 129..341
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
FT REGION 39..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 381 AA; 40465 MW; 8F21A903E7351249 CRC64;
MALVNRVSGF SSCSVSSHFG KAKTFGLNPI CSLNCTSSSS SSSSSSSSSS SSPFTEKHSV
ERYQRDSWVY NTQVEDASSW NLPFDSNSVR ENDIALQLPE LKKMLGVLRE KRESGGCDGG
GGSCGPGNVY LVGTGPGDPE LLTLKAVRVI QSAHLLLYDR LVSNDVLEFV GPDARLLYVG
KTAGYHSRTQ EEIHELLLSF AEAGATVVRL KGGDPLVFGR GGEEMDFLQK QGIQVKVIPG
ITAASGIAAE LGIPLTHRGI ANSVRFLTGH SRKGGTDPLF VAENAADPDS TLVVYMGLST
LPSLALKLMH HGLPSNTPAV AVERGTTPQQ RLVFAELKDL ADEISSAELV SPTLIVIGKV
VALSPFWPHS SIEASLLVEA K
//
