ID F6HDL1_VITVI Unreviewed; 579 AA.
AC F6HDL1;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=CNNM transmembrane domain-containing protein {ECO:0000259|PROSITE:PS51846};
GN OrderedLocusNames=VIT_05s0020g02610 {ECO:0000313|EMBL:CCB50382.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB50382.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FN595749; CCB50382.1; -; Genomic_DNA.
DR AlphaFoldDB; F6HDL1; -.
DR STRING; 29760.F6HDL1; -.
DR PaxDb; 29760-VIT_05s0020g02610-t01; -.
DR EnsemblPlants; Vitvi05g00420_t001; Vitvi05g00420_P001; Vitvi05g00420.
DR Gramene; Vitvi05g00420_t001; Vitvi05g00420_P001; Vitvi05g00420.
DR eggNOG; KOG2118; Eukaryota.
DR HOGENOM; CLU_011310_0_0_1; -.
DR InParanoid; F6HDL1; -.
DR Proteomes; UP000009183; Chromosome 5.
DR ExpressionAtlas; F6HDL1; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030026; P:intracellular manganese ion homeostasis; IBA:GO_Central.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR PANTHER; PTHR12064:SF97; METAL TRANSPORTER CNNM-5; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 108..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 104..286
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT REGION 533..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 579 AA; 63315 MW; D6F4A11F9A753929 CRC64;
MHEYTILPFY PLNQVSSQER RTESPYPAFN TCTGSTASLI LVLIRDTATL YQTRKREKGR
EKSLWSSDSL NLNSMQLINA VAIARMAARN LGAESLGGGD IAFGSLWFFI YVGICCFLVL
FAGIMSGLTL GLMSLGRVDL EILQRSGTSD EKKQAAAILP VVQKQHQLLV TLLLCNACSM
EALPLYLDKL FNQFVAIVLS VTFVLAFGEV IPQAICSRYG LSVGANFVWL VRILMIICYP
IAYPIGKILD WVLGHNEALF RRAQLKALVS IHGQEAGKGG ELTHDETTII SGALDLTEKT
AEEAMTPIES TFSLDVNSKL DWEAMGKILA RGHSRVPVYS GNPKNVIGLL LVKSLLTVRA
ETETPVSAVS IRRIPRVPAD MPLYDILNEF QKGSSHMAAV VKPKGRNKNA PQVMDGKITE
ENKITGADSQ LTTPLLSKQD EKLESIVVDI EKASRPTIIN RQSQHSDAAT NGLPRLSEDI
EDGEVIGIIT LEDVFEELLQ EEIVDETDEF VDVHKRIRVA AAAAASSIAR APSIRRLTGH
KGAGGQTKQV QSPKKSIEED SNSARLHGNP GESLLGNKR
//
