ID F6HNF2_VITVI Unreviewed; 636 AA.
AC F6HNF2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Transketolase-like pyrimidine-binding domain-containing protein {ECO:0000259|SMART:SM00861};
GN OrderedLocusNames=VIT_13s0019g04500 {ECO:0000313|EMBL:CCB56171.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB56171.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- COFACTOR:
CC Name=Co(2+); Xref=ChEBI:CHEBI:48828;
CC Evidence={ECO:0000256|ARBA:ARBA00001941};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- SIMILARITY: Belongs to the transketolase family.
CC {ECO:0000256|ARBA:ARBA00007131}.
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DR EMBL; FN595998; CCB56171.1; -; Genomic_DNA.
DR AlphaFoldDB; F6HNF2; -.
DR STRING; 29760.F6HNF2; -.
DR PaxDb; 29760-VIT_13s0019g04500-t01; -.
DR EnsemblPlants; Vitvi13g04177_t001; Vitvi13g04177_P001; Vitvi13g04177.
DR Gramene; Vitvi13g04177_t001; Vitvi13g04177_P001; Vitvi13g04177.
DR eggNOG; KOG0523; Eukaryota.
DR HOGENOM; CLU_009227_0_0_1; -.
DR InParanoid; F6HNF2; -.
DR Proteomes; UP000009183; Chromosome 13.
DR ExpressionAtlas; F6HNF2; baseline and differential.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004802; F:transketolase activity; IBA:GO_Central.
DR GO; GO:0006098; P:pentose-phosphate shunt; IBA:GO_Central.
DR CDD; cd07033; TPP_PYR_DXS_TK_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR InterPro; IPR033247; Transketolase_fam.
DR InterPro; IPR005474; Transketolase_N.
DR PANTHER; PTHR43522; TRANSKETOLASE; 1.
DR PANTHER; PTHR43522:SF5; TRANSKETOLASE; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR Pfam; PF00456; Transketolase_N; 2.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009183}.
FT DOMAIN 321..495
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 636 AA; 70610 MW; B1C972131F67ADFB CRC64;
MLIVDAVQTA KAGHSGMPLG MAKVGYILYR HVMRYNPRNP KWFNRDRFVL SAGHGCLLQY
ICLHLAGFQS VQLEDLQRLC LVVGPQVTLR MWLPMALKSL QAPWARFNKP DAVIVDHRTF
CIMGDGCVME GISHEAASLA AHWKLNKLTL IYDDNLNTID GATSLAFSED ISARFKALRW
NTITVDDTHN DMEAIKNALL SAFRETEKPT FIRVCKLSEK KGISKAHHGT FDEKDVKKMR
RKVSWSDREP FHVIPMIYRL VFKSAAGKCR YKQSMEWHSR LCYYQTKYPQ EFVEFKILLD
GGLLPGWESS LPKFPTSDPV DATQGYSEKC LSQLAKVLPG LIRGSADLAT SNKAYLHGHE
DFSQPNSPWG CNIRYGVREH AMAGISNGIA LHGSGLIPFA ATFLVFSDYM KNSIRLSALS
HAGVIYIMTH DSIGLGEDGP THQPAVEQLA GLRAVPQLLV FRPADGNETA GAYKVAVANR
NVPSLIALSR QKVAANLEGT SRASVERGGY IVSDNSEDKL PDIILIGTGS ELCLCDEGAK
MLRQEGRTVR VVSLVCWRLF DMQPQQYKEF VLPPSVSKRV SVEAASPIGW REYVGEEGVV
VGVEEFGASG AYLDTFKKFG FTEGNITRIA KSLLSQ
//
