ID F6HRG0_VITVI Unreviewed; 997 AA.
AC F6HRG0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 24-JAN-2024, entry version 74.
DE RecName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=VIT_19s0140g00200 {ECO:0000313|EMBL:CCB57268.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB57268.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SIMILARITY: Belongs to the peptidase C19 family.
CC {ECO:0000256|ARBA:ARBA00009085}.
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DR EMBL; FN596014; CCB57268.1; -; Genomic_DNA.
DR RefSeq; XP_010644793.1; XM_010646491.2.
DR RefSeq; XP_019072778.1; XM_019217233.1.
DR RefSeq; XP_019072779.1; XM_019217234.1.
DR AlphaFoldDB; F6HRG0; -.
DR STRING; 29760.F6HRG0; -.
DR PaxDb; 29760-VIT_19s0140g00200-t01; -.
DR EnsemblPlants; Vitvi19g01438_t001; Vitvi19g01438_P001; Vitvi19g01438.
DR GeneID; 100260067; -.
DR Gramene; Vitvi19g01438_t001; Vitvi19g01438_P001; Vitvi19g01438.
DR KEGG; vvi:100260067; -.
DR eggNOG; KOG1865; Eukaryota.
DR HOGENOM; CLU_007397_1_0_1; -.
DR InParanoid; F6HRG0; -.
DR OrthoDB; 227085at2759; -.
DR Proteomes; UP000009183; Chromosome 19.
DR ExpressionAtlas; F6HRG0; baseline and differential.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:EnsemblPlants.
DR GO; GO:0009908; P:flower development; IEA:EnsemblPlants.
DR GO; GO:0010154; P:fruit development; IEA:EnsemblPlants.
DR GO; GO:0048366; P:leaf development; IEA:EnsemblPlants.
DR GO; GO:0048364; P:root development; IEA:EnsemblPlants.
DR CDD; cd02661; Peptidase_C19E; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR24006:SF685; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15; 1.
DR Pfam; PF00443; UCH; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR PROSITE; PS00972; USP_1; 1.
DR PROSITE; PS50235; USP_3; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 76..113
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT DOMAIN 470..776
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 336..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 388..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 794..848
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..361
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..411
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 827..848
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 997 AA; 111387 MW; FA5738A3CED32BEC CRC64;
MLEPREADIP ALFLFLIVFP LVTYILLGKW SEVTKKKKRV SLLAQLAAEE AFKAEAMATA
SVMPLVSSSK SGNHECARCF GPATTRCSRC KSVRYCSGKC QIIHWRQVHK EECQQLETHS
SITSLKDAAI EESVHERVSV NDSMNSQFYG SGIKQTVLEK ASGNIINPSF STGMPATNAC
SSIDTSRITM MERRTGDKWV SRKSSREILK KEDVAICGST EEVSTSSNTS ITSSDDISLK
EAYTRQKLGN CDSVVSEEEM YKKYNFSAPT AFARGHTSSS MHERHKLQNQ NGNVFEPRSN
YGISSSCSEK NGTNGCEIER DHISCGGNLH REGITANDET GEPNCSPGIT SIKRSGKSKT
ALHTLGTKTT KSPKASMKLS REETCSEIER KGQTAEATRM SDSTPILAPG NNEVTSMGFM
KMMGLRKPLK PPKQDASEES SDIHKKIKML FPYEEFVRFF QCEVFNISPR GLLNCGNSCY
ANAVLQCLTC TKPLIIYLLQ RSHSRTCCVT NWCLMCELEK HVMMLRESGG PLSPSRILSH
MRSINCQIGD GSQEDAHEFL RLLVTSMQSI CLEKLGGERE VDARLQETTF IQHTFGGRLR
SKVKCLRCHL ESERYENIMD LTLEIFGWVE SLEDALTQFT TPEDLDGENM YRCRRCTTYV
RARKQLSIHE APNILTIVLK RFQEGRYGKI NKCITFPDML DMIPFMTGTY DVPPLYMLYA
VVVHMDTLNA SFSGHYVAYV KDLQGNWFRV DDAEVQPVST NQVMSEGAYI LFYMRSWPRP
PRAFPVKAIQ QQAPASAKHC SSKTHKSSRS KPRGDFVGLE PSNPKREVSP GFSSATSNGI
LRNGRNGSRT YVEPISQEFS DAPSSDWSLF TSSDEASFTT ESTRDSFSTV DYAETCNVDP
ISSIFNTSYM PEYASGNAVS CRMLSNGKLE TRYVQEKKGY VLDSYLPTQP DKAWKGENLK
QVSVSTEFPS DCNCGMSVKY GSNPKDTFVR TSGCCKL
//
