ID F6I0N4_VITVI Unreviewed; 671 AA.
AC F6I0N4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};
GN OrderedLocusNames=VIT_03s0038g04260 {ECO:0000313|EMBL:CCB60500.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB60500.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361221}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361221}.
CC -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC {ECO:0000256|ARBA:ARBA00009476, ECO:0000256|RuleBase:RU361221}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU361221}.
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DR EMBL; FN596508; CCB60500.1; -; Genomic_DNA.
DR AlphaFoldDB; F6I0N4; -.
DR STRING; 29760.F6I0N4; -.
DR PaxDb; 29760-VIT_03s0038g04260-t01; -.
DR EnsemblPlants; Vitvi03g00275_t001; Vitvi03g00275_P001; Vitvi03g00275.
DR Gramene; Vitvi03g00275_t001; Vitvi03g00275_P001; Vitvi03g00275.
DR eggNOG; KOG0475; Eukaryota.
DR HOGENOM; CLU_015263_3_0_1; -.
DR InParanoid; F6I0N4; -.
DR Proteomes; UP000009183; Chromosome 3.
DR ExpressionAtlas; F6I0N4; baseline and differential.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IBA:GO_Central.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:UniProtKB-UniRule.
DR CDD; cd04592; CBS_pair_voltage-gated_CLC_euk_bac; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Chloride {ECO:0000256|RuleBase:RU361221};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|RuleBase:RU361221};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361221};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361221};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361221}; Transport {ECO:0000256|RuleBase:RU361221}.
FT TRANSMEM 25..44
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 166..190
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 248..274
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 286..311
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 356..378
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 398..422
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT DOMAIN 523..579
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT REGION 449..476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..468
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 671 AA; 71549 MW; E499FAF32235938D CRC64;
MGKDEASKDD KKLRGMTSMI EEGNLAILSS CFVGLLTGIG IVLFNNAVHV IRDFSWDGIP
YRGASWLREE PIEAIWERVI LVPLCGGLLV SGLNVLRDAL QSPGDGNLIS NIKAALQPFL
KAVAACVTLG TGNSLGPEGP SVEIGASIAK GVSSLFDKSS KRKVSLVAAG SAAGISSGFN
AAFAGCFFAV ESVLWPSTAD SSLSLQNTTS MVILSAVIAS VVSEVGLGSE PAFKVPEYDF
RSPGELPLYL LLGILCGLVS LALSKCTSYM LVTIDNVHKA VGIPRAAFPV LGGLSVGLIA
LAYPEILYWG FENVDILLES RPFVKGLSAD LLLQLVAVKI VATSLCRASG LVGGYYAPSL
FIGAATGMAY GKFITFAISQ SNPMFHLSIL EVASPQAYGL VGMAATLAGV CQVPLTAVLL
LFELTQDYRI VLPLLGAVGL SSWTTSRQAK RKDVGDPGKL KEGNAQKTDL SSHDPSVLSS
SYSVAAKASH ASNLCEVESS LCVDDSNSET KELEKRIFVS QAMRTRYVTV LMSTLLIEAV
SLLLEEKQTC AVIVDDDHLL IGLLTLEDIQ EFSEREKARI RRSKEVLVSE MCSLDGEKCR
VPWTVTPGMN LFSAQMIMNT LGVNQLPVIS DHVEDHKGHP VGLLDRECIS LAFRAVAARE
YLSYVSTPEK A
//
