ID F6I6S7_VITVI Unreviewed; 515 AA.
AC F6I6S7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE RecName: Full=Flavin-containing monooxygenase {ECO:0000256|RuleBase:RU361177};
DE EC=1.-.-.- {ECO:0000256|RuleBase:RU361177};
GN OrderedLocusNames=VIT_18s0122g01430 {ECO:0000313|EMBL:CCB62645.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB62645.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|RuleBase:RU361177};
CC -!- SIMILARITY: Belongs to the FMO family. {ECO:0000256|ARBA:ARBA00009183,
CC ECO:0000256|RuleBase:RU361177}.
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DR EMBL; FN596759; CCB62645.1; -; Genomic_DNA.
DR AlphaFoldDB; F6I6S7; -.
DR STRING; 29760.F6I6S7; -.
DR PaxDb; 29760-VIT_18s0122g01430-t01; -.
DR EnsemblPlants; Vitvi18g00103_t001; Vitvi18g00103_P001; Vitvi18g00103.
DR Gramene; Vitvi18g00103_t001; Vitvi18g00103_P001; Vitvi18g00103.
DR eggNOG; KOG1399; Eukaryota.
DR HOGENOM; CLU_006909_9_3_1; -.
DR InParanoid; F6I6S7; -.
DR Proteomes; UP000009183; Chromosome 18.
DR ExpressionAtlas; F6I6S7; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000960; Flavin_mOase.
DR InterPro; IPR020946; Flavin_mOase-like.
DR PANTHER; PTHR23023; DIMETHYLANILINE MONOOXYGENASE; 1.
DR PANTHER; PTHR23023:SF217; FLAVIN-CONTAINING MONOOXYGENASE; 1.
DR Pfam; PF00743; FMO-like; 1.
DR PIRSF; PIRSF000332; FMO; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU361177};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU361177}; Membrane {ECO:0000256|SAM:Phobius};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000256|RuleBase:RU361177};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU361177};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 268..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 515 AA; 58911 MW; 682CAD04A01C1147 CRC64;
MEKRIAIVGA GISGLLACKY AMEKGFNPIV FEARSSIGGV WSQTIESTKL QTPISYYRFS
DFAWASSVTE TFPNHNQVME YLKSYALHFN ILPQIRFSSR VISIDYFTPR SEDFPSWDLW
GGTGKPFSPT GKWNITVKVT RHPLMVYEVD FVILCIGKYS DLPNIPDFPI NRGPDIFDGK
VIHSMDYAAM GGDLASEFIK EKRVTVVGLQ KSAVDVAAEV ATRNGEGHPC TLLFRRVHWL
VPEHFNTVSF QNLNRFSELM VHRPSEGFFL WLLAFLLSPL FWMFTKLVEI YLKWTYPLKK
YNMVPEHPFL KQIVSCMSMV IPANFYDRVR EGSLILKKAQ SFSFCRNGLV LDGEAAVLET
DIVIFATGYK SDEKLSNIFT STFFKNCITG SSAPFYRECI HPRIPQLAIL GYSESPSVLY
TMEVKSMWLA HFLAGNFKLP PVKEMEDDVM KWEKCNERYA GDGYKRSCVS VLLQIHVNDQ
LCRDMGCNPR RKRWFLPEMF AAYGPTDYAN LTWPG
//
