ID F6IM26_9SPHN Unreviewed; 642 AA.
AC F6IM26;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Propionyl-CoA synthetase {ECO:0000313|EMBL:CCA92478.1};
DE EC=6.2.1.17 {ECO:0000313|EMBL:CCA92478.1};
GN ORFNames=PP1Y_AT15964 {ECO:0000313|EMBL:CCA92478.1};
OS Novosphingobium sp. PP1Y.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=702113 {ECO:0000313|EMBL:CCA92478.1, ECO:0000313|Proteomes:UP000009242};
RN [1] {ECO:0000313|EMBL:CCA92478.1, ECO:0000313|Proteomes:UP000009242}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=sp. PP1Y {ECO:0000313|Proteomes:UP000009242};
RX PubMed=21685292; DOI=10.1128/JB.05349-11;
RA D'Argenio V., Petrillo M., Cantiello P., Naso B., Cozzuto L., Notomista E.,
RA Paolella G., Di Donato A., Salvatore F.;
RT "De novo sequencing and assembly of the whole genome of Novosphingobium sp.
RT strain PP1Y.";
RL J. Bacteriol. 193:4296-4296(2011).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; FR856862; CCA92478.1; -; Genomic_DNA.
DR RefSeq; WP_013832843.1; NC_015580.1.
DR AlphaFoldDB; F6IM26; -.
DR KEGG; npp:PP1Y_AT15964; -.
DR eggNOG; COG0365; Bacteria.
DR HOGENOM; CLU_000022_3_5_5; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000009242; Chromosome.
DR GO; GO:0050218; F:propionate-CoA ligase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Ligase {ECO:0000313|EMBL:CCA92478.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009242}.
FT DOMAIN 10..60
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 67..452
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 515..592
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 642 AA; 68991 MW; BB0028501E9D20EE CRC64;
MSDETGAVAY AGAVRRAAER PDQFWIEAAK AIGWVASPPR AYDQTKGWFP EGILNTCHNC
LDRHVQAGRG DVAALVYDSP VTGTIRRYTY RELLHETERA AAMLASLGAQ KGDRVILYMP
MIPETVFAML ACARLGVIHS VVFGGFAPPE LAKRIDDAAP KLVLTASCGI EGGRTIAYKP
LVDEALALAG HRVDHVVLVQ REQLAADLTP GRDIDWGDLR RQTADMAAPA CVPLASGDPL
YILYTSGTTG TPKGVVRDNG GHAVALAWSM ANIYGIGAGD TFWAASDVGW VVGHSYIVYG
PLLAGATTVL FEGKPVGTPD PGTFWRTIAR HDVKSFFTAP TAIRAIRKED PDARLLKEIG
TGACRAVFLA GERADPETIA WLERESGLPV IDHWWQTELG WPAIATCFAM GDLRRKAGSA
GFPVPGYQFA ILDDEGTALP DGASGNVVIK TPLPPGAFRS LWNNQATFAR NFATFPGYYE
TGDAGFRDQG GFLHIMGRTD DIINIAGHRL STGQMEEIVA RQLGVAECAV VGADDAIKGM
VPIAFVTPQT GYSADMSIAE RAVLAVRSEL GAIAAMRAVL VVDQLPKTRS GKILRSLLRK
IVNRESFDIP ATIDNPETPT KIIKIFDEHL GFNGHNPPNP GI
//
