ID F6PEJ8_DANRE Unreviewed; 328 AA.
AC F6PEJ8; A0A8M1QR11;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Sc:d0202 {ECO:0000313|Ensembl:ENSDARP00000116079};
DE SubName: Full=Vascular cell adhesion protein 1 {ECO:0000313|RefSeq:XP_001922015.4};
GN Name=si:ch211-74m13.1 {ECO:0000313|RefSeq:XP_001922015.4};
GN OrderedLocusNames=sc:d0202 {ECO:0000313|Ensembl:ENSDARP00000116079};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000116079};
RN [1] {ECO:0000313|Ensembl:ENSDARP00000116079}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000116079};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000116079, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000116079};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [3] {ECO:0000313|RefSeq:XP_001922015.4}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|RefSeq:XP_001922015.4};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CR381570; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CT573860; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_001922015.4; XM_001921980.7.
DR PaxDb; 7955-ENSDARP00000116079; -.
DR Ensembl; ENSDART00000142710; ENSDARP00000116079; ENSDARG00000095312.
DR Ensembl; ENSDART00000142710.3; ENSDARP00000116079.2; ENSDARG00000095312.3.
DR GeneID; 100149459; -.
DR KEGG; dre:100149459; -.
DR ZFIN; ZDB-GENE-080226-9; sc:d0202.
DR eggNOG; ENOG502RZRA; Eukaryota.
DR HOGENOM; CLU_073233_0_0_1; -.
DR OrthoDB; 4528282at2759; -.
DR TreeFam; TF333745; -.
DR Proteomes; UP000000437; Chromosome 3.
DR Bgee; ENSDARG00000095312; Expressed in mature ovarian follicle and 19 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005178; F:integrin binding; IEA:InterPro.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR047012; ICAM_VCAM.
DR InterPro; IPR003987; ICAM_VCAM_N.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR PANTHER; PTHR13771; INTERCELLULAR ADHESION MOLECULE; 1.
DR PANTHER; PTHR13771:SF9; INTERCELLULAR ADHESION MOLECULE 5; 1.
DR Pfam; PF13895; Ig_2; 1.
DR PRINTS; PR01472; ICAMVCAM1.
DR SMART; SM00409; IG; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..328
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041116919"
FT TRANSMEM 297..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 109..210
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 217..290
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 328 AA; 35817 MW; E0C236BD98AA5BDB CRC64;
MLQCVLGLFS AVTLLVTVKG TNAECPLQIN PPKLVVRFNS SASANCNTSV THDGMGWEAT
VGGVPLSKAN LITWRVSQLT DWKIEPPFCY INYGKQCEVP LPVTIYKTPD SVSISTVNQI
MTEGNQYELQ CDIHNVAPAQ NLTINWYKGE TLVNQTNFTD NTKSPVNKII RLLIHPDRAD
DGAQYRCETE LNLGVEGPQP PPKNTSKPLS IDVHYKPQHS SSAENISQSD TVYLNCTVKA
NPAAVYTWHS EHLKEKISSP VIQSSPLSPG KYTCTATNDL GASSKVFIVS SAGRTTFWAI
VIAGVVLAVL LIVSYVIFKI KSPPNTII
//
