ID F6PHB5_HORSE Unreviewed; 435 AA.
AC F6PHB5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Zinc finger CCCH-type containing 10 {ECO:0000313|Ensembl:ENSECAP00000010710.1};
GN Name=ZC3H10 {ECO:0000313|Ensembl:ENSECAP00000010710.1,
GN ECO:0000313|VGNC:VGNC:25162};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000010710.1, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000010710.1, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000010710.1,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000010710.1}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000010710.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_001504859.1; XM_001504809.3.
DR RefSeq; XP_005611355.1; XM_005611298.2.
DR AlphaFoldDB; F6PHB5; -.
DR STRING; 9796.ENSECAP00000010710; -.
DR PaxDb; 9796-ENSECAP00000010710; -.
DR Ensembl; ENSECAT00000013486.3; ENSECAP00000010710.1; ENSECAG00000013003.3.
DR Ensembl; ENSECAT00000082223.1; ENSECAP00000077917.1; ENSECAG00000013003.3.
DR Ensembl; ENSECAT00000102182.1; ENSECAP00000078625.1; ENSECAG00000013003.3.
DR VGNC; VGNC:25162; ZC3H10.
DR GeneTree; ENSGT00950000182897; -.
DR HOGENOM; CLU_039343_0_0_1; -.
DR InParanoid; F6PHB5; -.
DR OMA; MSGCLSI; -.
DR OrthoDB; 2881875at2759; -.
DR TreeFam; TF321931; -.
DR Proteomes; UP000002281; Chromosome 6.
DR Bgee; ENSECAG00000013003; Expressed in leukocyte and 23 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0043484; P:regulation of RNA splicing; IBA:GO_Central.
DR Gene3D; 3.30.1370.210; -; 2.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR12675; MUSCLEBLIND-LIKE PROTEIN; 1.
DR PANTHER; PTHR12675:SF6; ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 10; 1.
DR Pfam; PF00642; zf-CCCH; 2.
DR Pfam; PF14608; zf-CCCH_2; 1.
DR SMART; SM00356; ZnF_C3H1; 3.
DR PROSITE; PS50103; ZF_C3H1; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Reference proteome {ECO:0000313|Proteomes:UP000002281};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 36..63
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 73..99
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 134..161
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 36..63
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 73..99
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 134..161
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 165..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 315..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 238..272
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 188..217
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..362
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 435 AA; 46166 MW; E23FA91AEE31582D CRC64;
MPDRDSYANG TGSSSGGPGG GGSEEASGTG AGSGGASSDA ICRDFLRNVC KRGKRCRYRH
PDMSEVSNLG VSKNEFIFCH DFQNKECSRP NCRFIHGSKE DEDGYKKTGE LPPRLRQKVA
AGLGLSPADL PNGKEEVPIC RDFLKGDCQR GAKCKFRHLQ RDFEFDARGG GGTGGGGSTG
PVPPGRRHDL YDIYDLPDRG FEDHEPGPKR RRGGCCPPDG PHFESYEYSL APPRGVECRL
LEEENAMLRK RVEELKKQVS NLLATNEVLL EQNAQFRNQA KVMTLSSTAP ATEQTLAPTV
GTVATFNHGI AQTHTTLSSQ ALQPRPVSQQ ELVAPAGAPA APPTNAAPPA APPPPPPHLN
PEITPLSAAL AQTIAQGMAP PPVSMAPVAV SVAPVAPVAV SMAQPLAGIT MSHTTTPMVT
YPIASQSMRI TAMPH
//
