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Database: UniProt
Entry: F6PQA3_ORNAN
LinkDB: F6PQA3_ORNAN
Original site: F6PQA3_ORNAN 
ID   F6PQA3_ORNAN            Unreviewed;       301 AA.
AC   F6PQA3;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 2.
DT   31-JUL-2019, entry version 53.
DE   SubName: Full=ETS homologous factor {ECO:0000313|Ensembl:ENSOANP00000011769};
GN   Name=EHF {ECO:0000313|Ensembl:ENSOANP00000011769};
OS   Ornithorhynchus anatinus (Duckbill platypus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX   NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000011769, ECO:0000313|Proteomes:UP000002279};
RN   [1] {ECO:0000313|Ensembl:ENSOANP00000011769, ECO:0000313|Proteomes:UP000002279}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000011769,
RC   ECO:0000313|Proteomes:UP000002279};
RX   PubMed=18464734; DOI=10.1038/nature06936;
RA   Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E.,
RA   Ponting C.P., Grutzner F., Belov K., Miller W., Clarke L.,
RA   Chinwalla A.T., Yang S.P., Heger A., Locke D.P., Miethke P.,
RA   Waters P.D., Veyrunes F., Fulton L., Fulton B., Graves T., Wallis J.,
RA   Puente X.S., Lopez-Otin C., Ordonez G.R., Eichler E.E., Chen L.,
RA   Cheng Z., Deakin J.E., Alsop A., Thompson K., Kirby P.,
RA   Papenfuss A.T., Wakefield M.J., Olender T., Lancet D., Huttley G.A.,
RA   Smit A.F., Pask A., Temple-Smith P., Batzer M.A., Walker J.A.,
RA   Konkel M.K., Harris R.S., Whittington C.M., Wong E.S., Gemmell N.J.,
RA   Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J., Zemann A.,
RA   Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA   Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA   Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA   Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H.,
RA   Taylor J., Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y.,
RA   Huang X., Stark A., Kheradpour P., Kellis M., Flicek P., Chen Y.,
RA   Webber C., Hardison R., Nelson J., Hallsworth-Pepin K., Delehaunty K.,
RA   Markovic C., Minx P., Feng Y., Kremitzki C., Mitreva M., Glasscock J.,
RA   Wylie T., Wohldmann P., Thiru P., Nhan M.N., Pohl C.S., Smith S.M.,
RA   Hou S., Nefedov M., de Jong P.J., Renfree M.B., Mardis E.R.,
RA   Wilson R.K.;
RT   "Genome analysis of the platypus reveals unique signatures of
RT   evolution.";
RL   Nature 453:175-183(2008).
RN   [2] {ECO:0000313|Ensembl:ENSOANP00000011769}
RP   IDENTIFICATION.
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000011769};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family.
CC       {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594391}.
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DR   EMBL; AAPN01069839; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_001507939.2; XM_001507889.3.
DR   STRING; 9258.ENSOANP00000011769; -.
DR   Ensembl; ENSOANT00000011771; ENSOANP00000011769; ENSOANG00000007395.
DR   CTD; 26298; -.
DR   eggNOG; KOG3804; Eukaryota.
DR   eggNOG; ENOG4111K4J; LUCA.
DR   GeneTree; ENSGT00940000159310; -.
DR   InParanoid; F6PQA3; -.
DR   OrthoDB; 837296at2759; -.
DR   TreeFam; TF318679; -.
DR   Proteomes; UP000002279; Chromosome 3.
DR   Bgee; ENSOANG00000007395; Expressed in 4 organ(s), highest expression level in adult mammalian kidney.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0050673; P:epithelial cell proliferation; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR033071; EHF.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849:SF171; PTHR11849:SF171; 1.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002279};
KW   DNA-binding {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002279}.
FT   DOMAIN       31    117       PNT. {ECO:0000259|PROSITE:PS51433}.
FT   DOMAIN      208    290       ETS. {ECO:0000259|PROSITE:PS50061}.
FT   REGION      180    205       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    184    198       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   301 AA;  35136 MW;  9EBED2A1823FC6E2 CRC64;
     MIMILEGSGV MNLNPNSNLL HQQPSWTDGY PTCNVSNGFF GSQWHEIHPQ YWTKYQVWEW
     LQHLLDTNQL DASCIPFQEF DINGEHLCSM SLQEFTRAAG TAGQLLYSNL QHLKWNGQCG
     SDLFQSSHNI TVKTEQTDPS IIPPWKEENY LYDTNYGSTV ELLDSKSFCR AQISMTTTGH
     LPVDSPDMKK EQEHPPKSHT KKHNPRGTHL WEFIRDILLN PDKNPGLIKW EDRSEGIFRF
     LKSEAVAQLW GKKKNNSSMT YEKLSRAMRY YYKREILERV DGRRLVYKFG KNARGWRENE
     N
//
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