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Database: UniProt
Entry: F6PYN8_XENTR
LinkDB: F6PYN8_XENTR
Original site: F6PYN8_XENTR 
ID   F6PYN8_XENTR            Unreviewed;       302 AA.
AC   F6PYN8;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   16-OCT-2019, entry version 50.
DE   SubName: Full=ETS homologous factor {ECO:0000313|Ensembl:ENSXETP00000016466};
GN   Name=ehf {ECO:0000313|Ensembl:ENSXETP00000016466,
GN   ECO:0000313|Xenbase:XB-GENE-853705};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
OC   Silurana.
OX   NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000016466, ECO:0000313|Proteomes:UP000008143};
RN   [1] {ECO:0000313|Ensembl:ENSXETP00000016466}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000016466};
RX   PubMed=20431018; DOI=10.1126/science.1183670;
RA   Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA   Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L.,
RA   Blitz I.L., Blumberg B., Dichmann D.S., Dubchak I., Amaya E.,
RA   Detter J.C., Fletcher R., Gerhard D.S., Goodstein D., Graves T.,
RA   Grigoriev I.V., Grimwood J., Kawashima T., Lindquist E., Lucas S.M.,
RA   Mead P.E., Mitros T., Ogino H., Ohta Y., Poliakov A.V., Pollet N.,
RA   Robert J., Salamov A., Sater A.K., Schmutz J., Terry A., Vize P.D.,
RA   Warren W.C., Wells D., Wills A., Wilson R.K., Zimmerman L.B.,
RA   Zorn A.M., Grainger R., Grammer T., Khokha M.K., Richardson P.M.,
RA   Rokhsar D.S.;
RT   "The genome of the Western clawed frog Xenopus tropicalis.";
RL   Science 328:633-636(2010).
RN   [2] {ECO:0000313|Ensembl:ENSXETP00000016466}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2011) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family.
CC       {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594391}.
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DR   EMBL; AAMC01068942; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 8364.ENSXETP00000016466; -.
DR   PaxDb; F6PYN8; -.
DR   Ensembl; ENSXETT00000016466; ENSXETP00000016466; ENSXETG00000007559.
DR   Xenbase; XB-GENE-853705; ehf.
DR   eggNOG; KOG3804; Eukaryota.
DR   eggNOG; ENOG4111K4J; LUCA.
DR   GeneTree; ENSGT00940000159310; -.
DR   InParanoid; F6PYN8; -.
DR   OMA; QQVMDIH; -.
DR   TreeFam; TF318679; -.
DR   Proteomes; UP000008143; Unassembled WGS sequence.
DR   Bgee; ENSXETG00000007559; Expressed in 7 organ(s), highest expression level in embryo.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:InterPro.
DR   GO; GO:0050673; P:epithelial cell proliferation; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR033071; EHF.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849:SF171; PTHR11849:SF171; 1.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008143};
KW   DNA-binding {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT   DOMAIN       31    117       PNT. {ECO:0000259|PROSITE:PS51433}.
FT   DOMAIN      209    291       ETS. {ECO:0000259|PROSITE:PS50061}.
SQ   SEQUENCE   302 AA;  35275 MW;  DBC098DF6D6E1263 CRC64;
     MILQGNSIMN INHGTNPLVH QPAWNNPYPP CDALPTTGYF GGQWHDIHPQ YWSKFQVWEW
     LQQLVDTNQL DANCIPFHDF DIAGEHLCNM TLPDFTQAAG SAGHILYNNL QNLKWNGQCG
     SQMLQSFNVV IKTEQTEPSS MPPWKDEGYF YDNSYDGIIE MYESKPFCRN QHPLPSSSPY
     TMVYTEPDGK KVHEHPQKPS TKKHNPRGTH LWEFIRDILL TPEKNPGLIK WEDRSEGVFR
     FLKSEAVAQL WGKKKNNSSM TYEKLSRAMR YYYKREILER VDGRRLVYKF GRNARGWKEN
     EV
//
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