ID F6Q8L6_HORSE Unreviewed; 259 AA.
AC F6Q8L6;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=DCN1-like protein {ECO:0000256|RuleBase:RU363131};
DE AltName: Full=Defective in cullin neddylation protein 1-like protein {ECO:0000256|RuleBase:RU363131};
GN Name=DCUN1D1 {ECO:0000313|Ensembl:ENSECAP00000018953.2,
GN ECO:0000313|VGNC:VGNC:17062};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000018953.2, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000018953.2, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000018953.2,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000018953.2}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000018953.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; F6Q8L6; -.
DR SMR; F6Q8L6; -.
DR STRING; 9796.ENSECAP00000018953; -.
DR PaxDb; 9796-ENSECAP00000018953; -.
DR Ensembl; ENSECAT00000022906.3; ENSECAP00000018953.2; ENSECAG00000021365.3.
DR VGNC; VGNC:17062; DCUN1D1.
DR GeneTree; ENSGT00940000154552; -.
DR HOGENOM; CLU_047042_0_1_1; -.
DR InParanoid; F6Q8L6; -.
DR OMA; EKTAVNC; -.
DR TreeFam; TF313332; -.
DR Proteomes; UP000002281; Chromosome 19.
DR Bgee; ENSECAG00000021365; Expressed in gluteus medius and 23 other cell types or tissues.
DR GO; GO:0000151; C:ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0097602; F:cullin family protein binding; IBA:GO_Central.
DR GO; GO:0031624; F:ubiquitin conjugating enzyme binding; IBA:GO_Central.
DR GO; GO:0032182; F:ubiquitin-like protein binding; IBA:GO_Central.
DR GO; GO:0045116; P:protein neddylation; IBA:GO_Central.
DR Gene3D; 1.10.238.200; Cullin, PONY binding domain; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR014764; DCN-prot.
DR InterPro; IPR042460; DCN1-like_PONY.
DR InterPro; IPR005176; PONY_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR12281:SF10; DCN1-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR12281; RP42 RELATED; 1.
DR Pfam; PF03556; Cullin_binding; 1.
DR Pfam; PF14555; UBA_4; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51229; DCUN1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002281};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 60..248
FT /note="DCUN1"
FT /evidence="ECO:0000259|PROSITE:PS51229"
SQ SEQUENCE 259 AA; 30124 MW; F3709235E0610C54 CRC64;
MNKLKSSQKD KVRQFMIFTQ SSEKTAVSCL SQNDWKLDVA TDNFFQNPEL YIRESVKGSL
DRKKLEQLYN RYKDPQDENK IGIDGIQQFC DDLALDPASI SVLIIAWKFR AATQCEFSKQ
EFMDGMTELG CDSIEKLKAQ IPKMEQELKE PGRFKDFYQF TFNFAKNPGQ KGLDLEMAIA
YWNLVLNGRF KFLDLWNKFL LEHHKRSIPK DTWNLLLDFS TMIADDMSNY DEEGAWPVLI
DDFVEFARPQ IAGTKSTTV
//
