ID F6Q9R3_MONDO Unreviewed; 1991 AA.
AC F6Q9R3;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 2.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Transcription factor 20 {ECO:0000313|Ensembl:ENSMODP00000008669.4};
GN Name=TCF20 {ECO:0000313|Ensembl:ENSMODP00000008669.4};
OS Monodelphis domestica (Gray short-tailed opossum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
OX NCBI_TaxID=13616 {ECO:0000313|Ensembl:ENSMODP00000008669.4, ECO:0000313|Proteomes:UP000002280};
RN [1] {ECO:0000313|Ensembl:ENSMODP00000008669.4, ECO:0000313|Proteomes:UP000002280}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17495919; DOI=10.1038/nature05805;
RA Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., Duke S.,
RA Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., Kamal M.,
RA Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., Benos P.V.,
RA Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., Deakin J.E.,
RA Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., Gu W., Hore T.A.,
RA Huttley G.A., Kleber M., Jirtle R.L., Koina E., Lee J.T., Mahony S.,
RA Marra M.A., Miller R.D., Nicholls R.D., Oda M., Papenfuss A.T., Parra Z.E.,
RA Pollock D.D., Ray D.A., Schein J.E., Speed T.P., Thompson K.,
RA VandeBerg J.L., Wade C.M., Walker J.A., Waters P.D., Webber C.,
RA Weidman J.R., Xie X., Zody M.C., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Bloom T., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M.,
RA Samollow P.B., Lander E.S., Lindblad-Toh K.;
RT "Genome of the marsupial Monodelphis domestica reveals innovation in non-
RT coding sequences.";
RL Nature 447:167-177(2007).
RN [2] {ECO:0000313|Ensembl:ENSMODP00000008669.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007502864.1; XM_007502802.2.
DR RefSeq; XP_007502865.1; XM_007502803.2.
DR Ensembl; ENSMODT00000008840.5; ENSMODP00000008669.4; ENSMODG00000006993.5.
DR KEGG; mdo:100011852; -.
DR CTD; 6942; -.
DR eggNOG; KOG1084; Eukaryota.
DR GeneTree; ENSGT00940000157896; -.
DR HOGENOM; CLU_234705_0_0_1; -.
DR OrthoDB; 2919570at2759; -.
DR TreeFam; TF331317; -.
DR Proteomes; UP000002280; Chromosome 8.
DR Bgee; ENSMODG00000006993; Expressed in hindlimb bud and 17 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15699; ePHD_TCF20; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR041972; TCF-20_ePHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR14955; RETINOIC ACID INDUCED 1/TRANSCRIPTION FACTOR 20; 1.
DR PANTHER; PTHR14955:SF7; TRANSCRIPTION FACTOR 20; 1.
DR Pfam; PF13771; zf-HC5HC2H; 1.
DR SMART; SM00249; PHD; 1.
DR PROSITE; PS51805; EPHD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002280};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1860..1964
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT REGION 1..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 372..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..752
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 921..1082
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1110..1347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1385..1610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1660..1682
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1736..1867
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1971..1991
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..352
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..515
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..715
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 736..750
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1006..1020
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1049..1070
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1117..1138
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1178..1209
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1224..1250
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1274..1289
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1308..1322
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1422..1438
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1439..1456
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1555..1570
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1582..1597
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1747..1765
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1766..1787
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1788..1806
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1991 AA; 214587 MW; 71F4D58DE1BA212C CRC64;
MQSFREQSSY HGNQQSYPQE VHASSRLEEF SPRQQAQMFQ NFAGGGGGGS SSGGGSASGG
RRGATAAAAM AAEGSGHQSY QSFRKEAGEF YYMAGNKDPV TPGSQQPPQR RPSGPVQSYG
PPQGSSFGSQ YGGEGHVGQF QAQHSALGGV SHYQQDYSGP FSPGSTQYQQ QASSQQQQVQ
QLRQQLYQSH QPLPQASGQP ASSSSHLQPM QRPSALPSSS AGYQLRVGQF SQHYPSSAAA
SSSSFPSPQR FSQSGQNYDS SYNVTASSQY EGHTVGSSAQ AYGTQSNYNY QTPSMKNFEQ
SKLPQGGQQQ PQPQQQQQQP QQQQHPPQHT MPYGNTAPKL SMQSQVGQYS QPEVPVRSPM
QFHQNFSPIS NPSPAASVVQ SPSCSSTPSP LMQSGENLQC GQASMPMGSR NRILQMMPQL
SPTPSMMPSP NSHSTGFKGF GVEGMPEKRL TDPGLSSLSA LSTQVANLPN TVQHMLLSDA
LAPQKKNSKR SSSSSKKADS CTNSEGSSQP EEQLKSPMAE SLDGGCSSSS EDPGERVRQL
SGQSTSSDTT YKGGPLEKAN PSPPQSSQND PPKHSASPTV RDDATSPDEK DTSLSTDANL
KVNEKTIGVI VSREAMSGRG EKTGGQEKGS QDDDPAVPQA PPSTGGAKEP GHGAPPQPEP
QGGSKGNKSG DGSTNHNGEG NGQTGHSLSS GFTNRTEPSK SPGSLRYSYK DSLGSAMQRN
AGGFPQYPSG QEKGDYSGHG EQRKGRNEKF PSLLQEVLQG YHHHPDRRYS RNAQDHQGMA
GGLEGAMRPN VLISQTNELA SRGLLNKSIG SLLENPHWGP WDRKSSSSAP DMKQINLADY
PIPRKFEVES QASAHEPGGG LSERRSVICD ISPLRQLVRD PGAHTLGHMG ADGRMGRNER
LNPSLSQSVI LPGGLVSMET KLKSQSGQIK EEDFEQSKSQ ASINSKKSGD HCHPSGIKHE
SYRGNASPGA ATHDPLSEYG SPQDSRPTQM RRVPGRMGGR EGMRGRSPSQ YHDLTEKLKM
SPGRSRGPGG DPHHMNPHMA FERANRSSLH APFSPSSENL ASTYHTNTRP HAYGDPNPGL
NSQLHYKRQL YQQQEDYKDW SGSSAQGVIA AAQHRPEGPR KSPRQQQFLD RVRSPLKNDK
DGMMYGPPSS YHDPGNPESG RCLMANDGVP SNKGIDLKHS AQKLQQESCW DLSRQTSPAK
SSGPSGMSSQ KRYGPPHEAD GHGLSESAQS SKPGNVMLRL PGQEDQSPQN PLIMRRRVRS
FISPIPSKRQ SQDVKNSGTE DKGRLLPPSK EGADKAFNSY AHVAHNQDVK SVPKRESSKD
LVSPDSRSCP AVSLTSPTKT KILPPRKGRG LKLEAIVQKI TSPNIRRSAP SNSAEVGGDT
VTLDDILALK SGPPEGGSTA SHEADAVEKR KGEVAVSDLG GPASQDLNNE ASLSRSSEDW
RGSGDDKVKK ETLPEPGTSG KDAPGVMAPP TSQKPMGSQG RPDGTLAGSG PLSFPDSKSV
SPAGISAPEP NAKSEEKEGE AVTVSPKQEC FPPKGYFPSG KKKGRPIGSV NKQKKQQPPP
PPPPPTQVPE GSGDGEPKPK KQRQRRERRK PGAQPRKRKT KQAVPIVEPQ EPEIKLKYAT
QPLDKSDAKN KSFFPYIHVV NKCEIGAVCT IINAEEEEQS KLVKGRKGQR SLTPPPSSVE
SKVLPTSSFV LQGPVVTESS VLGHLVCCLC GKWASYRNMG DLFGPFYPQD YVATLPKNPP
PKRATEMQNK VKVRHKSAPN GCAKTDTEEE EEEEEEEEEE EEEEEQQQQQ QQQPLPAPSQ
QKEQRSLAAH PRFKRRHRSE DCSGTPRSLS RGIPCKKATI EGGSGSGNEK TPSDSKPAGP
VSEGAGPELE LHIPELPLDS NELWVHEGCV LWANGIYLVC GRLYGLQEAL EIAREMKCSH
CQEPGATLGC YNKGCSFRYH YPCAIDADCL LNEENFSVRC PKHKPPLPCS LPPLQNKTVK
GSLGTEQSER G
//
