ID F6QPU5_MOUSE Unreviewed; 249 AA.
AC F6QPU5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 2.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=G protein subunit alpha transducin 2 {ECO:0000313|Ensembl:ENSMUSP00000121533.3};
DE Flags: Fragment;
GN Name=Gnat2 {ECO:0000313|Ensembl:ENSMUSP00000121533.3,
GN ECO:0000313|MGI:MGI:95779};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000121533.3, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000121533.3, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000121533.3,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000121533.3}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000121533.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6QPU5; -.
DR SMR; F6QPU5; -.
DR jPOST; F6QPU5; -.
DR MaxQB; F6QPU5; -.
DR PeptideAtlas; F6QPU5; -.
DR ProteomicsDB; 320615; -.
DR Antibodypedia; 33764; 207 antibodies from 26 providers.
DR Ensembl; ENSMUST00000131856.3; ENSMUSP00000121533.3; ENSMUSG00000009108.16.
DR AGR; MGI:95779; -.
DR MGI; MGI:95779; Gnat2.
DR VEuPathDB; HostDB:ENSMUSG00000009108; -.
DR GeneTree; ENSGT00940000158399; -.
DR Proteomes; UP000000589; Chromosome 3.
DR Bgee; ENSMUSG00000009108; Expressed in retinal neural layer and 98 other cell types or tissues.
DR ExpressionAtlas; F6QPU5; baseline and differential.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF68; GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-2; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 1: Evidence at protein level;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Proteomics identification {ECO:0007829|ProteomicsDB:F6QPU5};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT REGION 61..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 249
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000121533.3"
SQ SEQUENCE 249 AA; 28091 MW; 489E056401191F18 CRC64;
MKIIHQDGYS PEECLEFKSV IYGNVLQSIL AIIRAMSTLG IDYAEPSCAV RDSCYLVQGG
SRRRSRPETG RPQGESGVRS NARCFPLSKF PEPAWKATDL LPAHSQSDFW ITQDAGRQLN
NLADSTEEGT MPPELVDVIR KLWKDGGVQA CFDRAAEFQL NDSASYYLNQ LDRITDPNYL
PNEQDVLRSR VKTTGIIETK FSVKDLNFRM FDVGGQRSER KKWIHCFEGV TCIIFCAALS
AYDMVLVED
//
