ID F6QX57_ORNAN Unreviewed; 791 AA.
AC F6QX57;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Tubulin tyrosine ligase like 13 {ECO:0000313|Ensembl:ENSOANP00000010904.3};
GN Name=TTLL13 {ECO:0000313|Ensembl:ENSOANP00000010904.3};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000010904.3, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000010904.3, ECO:0000313|Proteomes:UP000002279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000010904.3,
RC ECO:0000313|Proteomes:UP000002279};
RX PubMed=18464734; DOI=10.1038/nature06936;
RA Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E., Ponting C.P.,
RA Grutzner F., Belov K., Miller W., Clarke L., Chinwalla A.T., Yang S.P.,
RA Heger A., Locke D.P., Miethke P., Waters P.D., Veyrunes F., Fulton L.,
RA Fulton B., Graves T., Wallis J., Puente X.S., Lopez-Otin C., Ordonez G.R.,
RA Eichler E.E., Chen L., Cheng Z., Deakin J.E., Alsop A., Thompson K.,
RA Kirby P., Papenfuss A.T., Wakefield M.J., Olender T., Lancet D.,
RA Huttley G.A., Smit A.F., Pask A., Temple-Smith P., Batzer M.A.,
RA Walker J.A., Konkel M.K., Harris R.S., Whittington C.M., Wong E.S.,
RA Gemmell N.J., Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J.,
RA Zemann A., Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H., Taylor J.,
RA Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y., Huang X., Stark A.,
RA Kheradpour P., Kellis M., Flicek P., Chen Y., Webber C., Hardison R.,
RA Nelson J., Hallsworth-Pepin K., Delehaunty K., Markovic C., Minx P.,
RA Feng Y., Kremitzki C., Mitreva M., Glasscock J., Wylie T., Wohldmann P.,
RA Thiru P., Nhan M.N., Pohl C.S., Smith S.M., Hou S., Nefedov M.,
RA de Jong P.J., Renfree M.B., Mardis E.R., Wilson R.K.;
RT "Genome analysis of the platypus reveals unique signatures of evolution.";
RL Nature 453:175-183(2008).
RN [2] {ECO:0000313|Ensembl:ENSOANP00000010904.3}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000010904.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6QX57; -.
DR Ensembl; ENSOANT00000010906.3; ENSOANP00000010904.3; ENSOANG00000006840.3.
DR eggNOG; KOG2158; Eukaryota.
DR GeneTree; ENSGT00940000161367; -.
DR HOGENOM; CLU_010131_1_1_1; -.
DR InParanoid; F6QX57; -.
DR OMA; HSWCHLQ; -.
DR TreeFam; TF313087; -.
DR Proteomes; UP000002279; Chromosome X1.
DR Bgee; ENSOANG00000006840; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0005929; C:cilium; IBA:GO_Central.
DR GO; GO:0015631; F:tubulin binding; IBA:GO_Central.
DR GO; GO:0070740; F:tubulin-glutamic acid ligase activity; IBA:GO_Central.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IBA:GO_Central.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR004344; TTL/TTLL_fam.
DR PANTHER; PTHR12241; TUBULIN POLYGLUTAMYLASE; 1.
DR PANTHER; PTHR12241:SF91; TUBULIN POLYGLUTAMYLASE TTLL13; 1.
DR Pfam; PF03133; TTL; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR PROSITE; PS51221; TTL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002279}.
FT REGION 505..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 685..717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 791 AA; 89578 MW; 91C2B48623ABFA8E CRC64;
MTHSKHLLNT IIMMTIQSSP KPSAQGLSPA GLGFLDPLFP PAPSFCPALP AHPRLTFPSP
LHPPPFCRLL AINLTNCKYE SVRRAARLCG LQEVGEDEEW TVYWTDCSVS LERVMYMKRF
QKINHFPGMT EICRKDLLAR NLNRMYKLHP AEYNIFPRTW CLPADYGDFQ AHGRLRKSRT
YICKPDSGCR GRGIFITRNP REIKPGEHMI CQQYISKPFL VDGFKFDLRV YVLITSCDPL
RIFVYEEGLA RFATLPYVEP SVGNLDDVCM HLTNYAINKN NENFIRDSTT GSKRKLSTLN
AWLKEHSFDS SKLWEDIEDV IIKTVISAHS VLRHNYRTCF PQHLGGGTCA CFEILGFDIL
LDRKLKPWLL EVNHSPSFTT DSRLDREVKD ALLCDAMTLV NLQSCDKKKV LEEDKRRVKE
RLTQGHQPPR EARREQMELS NAIWLDQEIK YEDSHLGGYR RIYPGPNADK YTPFFKYNGS
LFQETAASKA REECARQQLE EIRLKQEQRE VSGKRKKDKE ASQGEQTQEK ARPWTGAKGP
LPPQLNTMKP QDIVEEEELE RMRALLQRED LIRSLGIADH LSRLLGSKYQ PQARFPERQV
RPRFLQDVFG GRELHATVNL VPLTILRTRS IQLDPELSPL TRPRHFSPSI LGPLAGMRVT
VPHSSQCHLD PKSLSWVRGT SVVNPPRPLA AKKAEGHQSA SARGRLENRD QSSSGLEAVS
RSLAGLVPVS LTPGRSYPRP AREAGAAWAG FSTGTHLPGG PPARARLPSP ASSLLLQSSA
ALSLFDINCP R
//
