ID F6R046_CIOIN Unreviewed; 341 AA.
AC F6R046;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 2.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=N-acetyl-D-glucosamine kinase {ECO:0000256|ARBA:ARBA00014974};
DE EC=2.7.1.59 {ECO:0000256|ARBA:ARBA00012122};
DE AltName: Full=GlcNAc kinase {ECO:0000256|ARBA:ARBA00031123};
GN Name=LOC100183285 {ECO:0000313|Ensembl:ENSCINP00000020093.3};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000020093.3, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000020093.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic-type N-acetylglucosamine kinase
CC family. {ECO:0000256|ARBA:ARBA00006198}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EAAA01002140; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; F6R046; -.
DR STRING; 7719.ENSCINP00000020093; -.
DR Ensembl; ENSCINT00000020093.3; ENSCINP00000020093.3; ENSCING00000009973.3.
DR GeneTree; ENSGT00510000047418; -.
DR HOGENOM; CLU_016274_0_0_1; -.
DR InParanoid; F6R046; -.
DR OMA; IETRYDM; -.
DR TreeFam; TF314158; -.
DR Proteomes; UP000008144; Chromosome 5.
DR GO; GO:0045127; F:N-acetylglucosamine kinase activity; IBA:GO_Central.
DR Gene3D; 3.30.420.40; -; 1.
DR InterPro; IPR002731; ATPase_BadF.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR039758; NAGK_prok_euk.
DR PANTHER; PTHR12862; BADF TYPE ATPASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12862:SF0; N-ACETYL-D-GLUCOSAMINE KINASE; 1.
DR Pfam; PF01869; BcrAD_BadFG; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008144}.
FT DOMAIN 7..316
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
SQ SEQUENCE 341 AA; 36573 MW; CC5CAECD525787D4 CRC64;
SMPFFGGIEG GGSKSSMIII DENGKCVGES SGPDTNVWQI GATEVSNRIN KMVIDAKNVA
GIPTDQKLAS LGMCLSGGEQ PATNKEMIKT MSELYPLMSE SLIIKSDTAG SIATACEKGG
MVLISGTGSN CSLENEDGST FGCGGWGHMM GDEGGAYWIS HRAVKYVFDH DDNMDSAPCD
PTLVRKMMYK YFKVSDRQGM LNSLYSDFSK SNFAGFCKVL AVEGCVKKSD ALCLHLFKEA
GIVLAKHIIA LVPKADKAML QRADGLQVVC VGSVWKNWKY IKEAFMETLS SHLQGKVSSI
TLVELNGNSA IGSAVIGAKH ANIPISVDLS KNYRVLYQST I
//
