ID F6R901_CIOIN Unreviewed; 835 AA.
AC F6R901;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 3 {ECO:0000256|ARBA:ARBA00020976};
DE AltName: Full=Component of oligomeric Golgi complex 3 {ECO:0000256|ARBA:ARBA00031339};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000009990.3, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000009990.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Involved in ER-Golgi transport.
CC {ECO:0000256|ARBA:ARBA00002090}.
CC -!- SIMILARITY: Belongs to the COG3 family.
CC {ECO:0000256|ARBA:ARBA00009936}.
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DR EMBL; EAAA01002581; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; F6R901; -.
DR STRING; 7719.ENSCINP00000009990; -.
DR Ensembl; ENSCINT00000009990.3; ENSCINP00000009990.3; ENSCING00000004827.3.
DR GeneTree; ENSGT00390000015682; -.
DR HOGENOM; CLU_011639_1_1_1; -.
DR InParanoid; F6R901; -.
DR OMA; DEFELWG; -.
DR TreeFam; TF314200; -.
DR Proteomes; UP000008144; Chromosome 8.
DR GO; GO:0005801; C:cis-Golgi network; IEA:InterPro.
DR GO; GO:0017119; C:Golgi transport complex; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR InterPro; IPR048685; COG3_C.
DR InterPro; IPR048320; COG3_N.
DR InterPro; IPR007265; COG_su3.
DR PANTHER; PTHR13302; CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3; 1.
DR PANTHER; PTHR13302:SF8; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3; 1.
DR Pfam; PF20671; COG3_C; 1.
DR Pfam; PF04136; COG3_N; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000008144};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 124..266
FT /note="Conserved oligomeric Golgi complex subunit 3 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF04136"
FT DOMAIN 288..647
FT /note="Conserved oligomeric Golgi complex subunit 3 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF20671"
FT REGION 513..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..533
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 835 AA; 95201 MW; 8FCA2EDBE294AD80 CRC64;
SSLMASDHIS TISTMERLSL WNATDNTGLA TLNELQQDSF LELAAIGSNR ALPIEVPLTE
PVNITPNVLD SHAIPGSVED VLTKGFTKLG MAGEKIENAQ QFYSWFSQIE EEVRSVERKR
FTEHVETLKQ HREYCQYITQ DVNKALQYLD DLEKEYVYVS TKSNALHEAC EHLLADQTAL
FSVAETIHEN LDYFNEVSRM NTKLSSPNIS VTSEDFRSML SKIEECIEFM QAHPAYKDSA
EYVIKYKTCL TKALGMIKLY VVNSLESTKQ AILNRKSEAF GSGNDAFTLY YGKFRTNAPK
IKALMEQIEQ RSVCSQEYQQ IVVDIHQCYF TQRETLLSPS VTSAMLELLN ANKQDHCALV
RSGCSFMVHV CEDEHQLYGH FFSSQSKKLY EMLLRLCGNL YDMLRPLIIH VYHLETLAEL
CNILKMEMID DHVQNNPEQL QAFHSVALQM LEDVQERLVF RANIHIRDDI RGYKPSPGDI
MYPEKLEMME EIARNIKASA KVEKDTFTEI QLTESPQDSL SDVDVASSSK SSNGKLDEKF
HTSPADMHGM WYPTVRRVLV CLSKLYRCID KAIFQGLSQE ALEACVRSLV EASNMIKARA
PLKPGSSENR TTDAQLFLIK HLLILREQIA PFQAEFAIRE TQLDFSRTKD AAFRFVLEPK
LIPNLLSVSS NALLQFVYEG APEVKEFYID SKKDVDRQLK SVCENFIEHQ TMLYCQPLSE
FLQKASKLVS MNQEDSNVSV SLRQQDFASA EQVQQLVGGV YRNLKLMVKK TAYVMSLYLA
NKETEKILFK PIKLNVQHVF QQLNMLLLEN YSDEDKAIIA APTSDQIALL MSTAF
//
